CAS 53-34-9|Fluprednisolone

Introduction：Basic information about CAS 53-34-9|Fluprednisolone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Fluprednisolone BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Fluprednisolone
CAS Number	53-34-9	Molecular Weight	378.43400
Density	1.35 g/cm3	Boiling Point	572.3ºC at 760 mmHg
Molecular Formula	C₂₁H₂₇FO₅	Melting Point	208 - 213ºC
MSDS	/	Flash Point	299.9ºC

Names

Name	(6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
Synonym	More Synonyms

Fluprednisolone BiologicalActivity

Description	6α-Fluoroprednisolone (Fluprednisolone) is an internal standard for methylprednisolone, prednisolone and prednisone. 6α-Fluoroprednisolone is an anti-inflammatory agent. 6α-Fluoroprednisolone can be used for congenital adrenal virilism and Addison's disease research[1][2][3].
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
References	[1]. Schmidt KS, et al. In-house validation and factorial effect analysis of a liquid chromatography-tandem mass spectrometry method for the determination of corticosteroids in bovine and porcine muscle tissue. Anal Bioanal Chem. 2013 Jul;405(19):6287-97. [2]. Laron Z, et al. The comparative effect of 6 alpha-fluoroprednisolone, 6 alpha-methylprednisolone, and hydrocortisone on linear growth of children with congenital adrenal virilism and Addison's disease. J Pediatr. 1968 Nov;73(5):774-82. [3]. COLLINS EJ, et al. Influence of adrenal steroids on radio-calcium metabolism in young beagle dogs. Acta Endocrinol (Copenh). 1963 Mar;42:348-54.

Description

6α-Fluoroprednisolone (Fluprednisolone) is an internal standard for methylprednisolone, prednisolone and prednisone. 6α-Fluoroprednisolone is an anti-inflammatory agent. 6α-Fluoroprednisolone can be used for congenital adrenal virilism and Addison's disease research[1][2][3].

Related Catalog

Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology

References

[1]. Schmidt KS, et al. In-house validation and factorial effect analysis of a liquid chromatography-tandem mass spectrometry method for the determination of corticosteroids in bovine and porcine muscle tissue. Anal Bioanal Chem. 2013 Jul;405(19):6287-97.

[2]. Laron Z, et al. The comparative effect of 6 alpha-fluoroprednisolone, 6 alpha-methylprednisolone, and hydrocortisone on linear growth of children with congenital adrenal virilism and Addison's disease. J Pediatr. 1968 Nov;73(5):774-82.

[3]. COLLINS EJ, et al. Influence of adrenal steroids on radio-calcium metabolism in young beagle dogs. Acta Endocrinol (Copenh). 1963 Mar;42:348-54.

Chemical & Physical Properties

Density	1.35 g/cm3
Boiling Point	572.3ºC at 760 mmHg
Melting Point	208 - 213ºC
Molecular Formula	C₂₁H₂₇FO₅
Molecular Weight	378.43400
Flash Point	299.9ºC
Exact Mass	378.18400
PSA	94.83000
LogP	1.50560
Index of Refraction	1.597
InChIKey	MYYIMZRZXIQBGI-HVIRSNARSA-N
SMILES	CC12C=CC(=O)C=C1C(F)CC1C2C(O)CC2(C)C1CCC2(O)C(=O)CO

Synonyms

F. I. 6150

fluprednisolone

EINECS 200-170-8

MFCD00200355

Isopredon

Prednisolone,6alpha-fluoro

6alpha-Fluoroprednisolone

Etadrol

Vladicort

Alphadrol

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