CAS 59729-31-6|Lorcainide

Introduction：Basic information about CAS 59729-31-6|Lorcainide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Synonyms

Common Name	Lorcainide
CAS Number	59729-31-6	Molecular Weight	370.91600
Density	1.161g/cm3	Boiling Point	503ºC at 760 mmHg
Molecular Formula	C₂₂H₂₇ClN₂O	Melting Point	/
MSDS	/	Flash Point	258ºC

Names

Name	N-(4-chlorophenyl)-2-phenyl-N-(1-propan-2-ylpiperidin-4-yl)acetamide
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.161g/cm3
Boiling Point	503ºC at 760 mmHg
Molecular Formula	C₂₂H₂₇ClN₂O
Molecular Weight	370.91600
Flash Point	258ºC
Exact Mass	370.18100
PSA	23.55000
LogP	4.72640
Index of Refraction	1.594
InChIKey	XHOJAWVAWFHGHL-UHFFFAOYSA-N
SMILES	CC(C)N1CCC(N(C(=O)Cc2ccccc2)c2ccc(Cl)cc2)CC1
Storage condition	2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CY1483600

CHEMICAL NAME :: Benzeneacetamide, N-(4-chlorophenyl)-N-(1-(1-methylethyl)-4-piperidinyl )-

CAS REGISTRY NUMBER :: 59729-31-6

BEILSTEIN REFERENCE NO. :: 0497568

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C22-H27-Cl-N2-O

MOLECULAR WEIGHT :: 370.96

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - woman

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - coma Cardiac - pulse rate

REFERENCE :: JTCTDW Journal of Toxicology, Clinical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.19- 1982- Volume(issue)/page/year: 33,157,1995

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 395 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RMISDU International Congress and Symposium Series - Royal Society of Medicine Services Limited. (Royal Society of Medicine Services Ltd., 7E. 60th St., New York, NY 10022) No.1- 1978- Volume(issue)/page/year: 49,23,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 18600 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RMISDU International Congress and Symposium Series - Royal Society of Medicine Services Limited. (Royal Society of Medicine Services Ltd., 7E. 60th St., New York, NY 10022) No.1- 1978- Volume(issue)/page/year: 49,23,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 483 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RMISDU International Congress and Symposium Series - Royal Society of Medicine Services Limited. (Royal Society of Medicine Services Ltd., 7E. 60th St., New York, NY 10022) No.1- 1978- Volume(issue)/page/year: 49,23,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 18800 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RMISDU International Congress and Symposium Series - Royal Society of Medicine Services Limited. (Royal Society of Medicine Services Ltd., 7E. 60th St., New York, NY 10022) No.1- 1978- Volume(issue)/page/year: 49,23,1981

Safety Information

Hazard Codes	Xn
Safety Phrases	26-36/37

Synonyms

Lorcainidum [INN-Latin]

Benzeneacetamide,N-(4-chlorophenyl)-N-[1-(1-methylethyl)-4-piperidinyl]

N-(4-chloro-phenyl)-N-(1-isopropyl-piperidin-4-yl)-2-phenyl-acetamide

LORCAINIDE

N-(4-chlorophenyl)-N-[1-(1-methylethyl)-4-piperidinyl]benzeneacetamide

Lorcainida [INN-Spanish]

4'-Chloro-N-(1-isopropyl-4-piperidyl)-2-phenylacetanilide

Lorcainide [INN:BAN]

lorcainid

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