CAS 80734-02-7|Lenampicillin hydrochloride

Introduction:Basic information about CAS 80734-02-7|Lenampicillin hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameLenampicillin hydrochloride
CAS Number80734-02-7Molecular Weight497.95
Density/Boiling Point717.4ºC at 760 mmHg
Molecular FormulaC21H24ClN3O7SMelting Point/
MSDS/Flash Point387.7ºC

Names

Name(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate,hydrochloride
SynonymMore Synonyms

Lenampicillin hydrochloride BiologicalActivity

DescriptionLenampicillin (hydrochloride) is the efficient prodrug of ampicillin (ABPC ) in terms of the enhancement of absorption and decrease of side effects.In vivo : The intestinal absorption of LAPC is satisfactory in view of the urinary excretion of metabolites, accounting for 93% of dose in human, 74% in dogs and 55% in rats, respectively.
Related CatalogSignaling Pathways >>Anti-infection >>BacterialResearch Areas >>Cancer
References

[1]. Awata N et al. [Metabolism of lenampicillin hydrochloride. II. Metabolism of promoiety]. Jpn J Antibiot. 1985 Jul;38(7):1785-93.

[2]. Awata N et al. [Metabolism of lenampicillin hydrochloride. I. Metabolism of ampicillin structure]. Jpn J Antibiot. 1985 Jul;38(7):1776-84.

Chemical & Physical Properties

Boiling Point717.4ºC at 760 mmHg
Molecular FormulaC21H24ClN3O7S
Molecular Weight497.95
Flash Point387.7ºC
PSA170.38000
LogP1.86060
InChIKeyFXXSETTYJSGMCR-GLCLSGQWSA-N
SMILESCc1oc(=O)oc1COC(=O)C1N2C(=O)C(NC(=O)C(N)c3ccccc3)C2SC1(C)C.Cl
Storage condition2-8℃

Synonyms

lenampicillin hydrochloride
Lenampicillin hydrochloride (JP16)
Valacillin (TN)
Lenampicillin (hydrochloride)
CAS 3690-04-8|AMINOPROPYLON
CAS 16143-80-9|sodium tris(1,2-naphthoquinone 1-oximato-O,O')ferrate(1-)
Recommended......
TOP