Introduction:Basic information about CAS 80734-02-7|Lenampicillin hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Lenampicillin hydrochloride |
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| CAS Number | 80734-02-7 | Molecular Weight | 497.95 |
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| Density | / | Boiling Point | 717.4ºC at 760 mmHg |
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| Molecular Formula | C21H24ClN3O7S | Melting Point | / |
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| MSDS | / | Flash Point | 387.7ºC |
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Names
| Name | (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate,hydrochloride |
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| Synonym | More Synonyms |
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Lenampicillin hydrochloride BiologicalActivity
| Description | Lenampicillin (hydrochloride) is the efficient prodrug of ampicillin (ABPC ) in terms of the enhancement of absorption and decrease of side effects.In vivo : The intestinal absorption of LAPC is satisfactory in view of the urinary excretion of metabolites, accounting for 93% of dose in human, 74% in dogs and 55% in rats, respectively. |
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| Related Catalog | Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>Cancer |
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| References | [1]. Awata N et al. [Metabolism of lenampicillin hydrochloride. II. Metabolism of promoiety]. Jpn J Antibiot. 1985 Jul;38(7):1785-93. [2]. Awata N et al. [Metabolism of lenampicillin hydrochloride. I. Metabolism of ampicillin structure]. Jpn J Antibiot. 1985 Jul;38(7):1776-84. |
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Chemical & Physical Properties
| Boiling Point | 717.4ºC at 760 mmHg |
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| Molecular Formula | C21H24ClN3O7S |
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| Molecular Weight | 497.95 |
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| Flash Point | 387.7ºC |
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| PSA | 170.38000 |
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| LogP | 1.86060 |
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| InChIKey | FXXSETTYJSGMCR-GLCLSGQWSA-N |
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| SMILES | Cc1oc(=O)oc1COC(=O)C1N2C(=O)C(NC(=O)C(N)c3ccccc3)C2SC1(C)C.Cl |
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| Storage condition | 2-8℃ |
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Synonyms
| lenampicillin hydrochloride |
| Lenampicillin hydrochloride (JP16) |
| Valacillin (TN) |
| Lenampicillin (hydrochloride) |