Introduction：Basic information about CAS 19881-70-0|Windorphen, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Windorphen |
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| CAS Number | 19881-70-0 | Molecular Weight | 302.75 |
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| Density | 1.198g/cm3 | Boiling Point | 468.1ºC at 760mmHg |
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| Molecular Formula | C17H15ClO3 | Melting Point | 160-163ºC |
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| MSDS | USA | Flash Point | 184.7ºC |
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Names
| Name | 3-Chloro-2,3-bis(4-methoxyphenyl)acrylaldehyde |
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| Synonym | More Synonyms |
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Windorphen BiologicalActivity
| Description | Windorphen is a Wnt/β-catenin signal inhibitor that specifically targets the function of the c-terminal transactivation domain of β-catenin-1 but not β-catenin-2. Windorphen selectively targets p300, disrupting the association of the mammalian β-catenin with p300 but not CBP[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Stem Cell/Wnt >>WntSignaling Pathways >>Epigenetics >>Histone Acetyltransferase |
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| References | [1]. Jijun Hao, et al. Selective small molecule targeting β-catenin function discovered by in vivo chemical genetic screen. Cell Rep. 2013 Sep 12;4(5):898-904. |
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Chemical & Physical Properties
| Density | 1.198g/cm3 |
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| Boiling Point | 468.1ºC at 760mmHg |
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| Melting Point | 160-163ºC |
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| Molecular Formula | C17H15ClO3 |
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| Molecular Weight | 302.75 |
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| Flash Point | 184.7ºC |
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| Exact Mass | 302.07100 |
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| PSA | 35.53000 |
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| LogP | 4.00980 |
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| Vapour Pressure | 6.15E-09mmHg at 25°C |
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| Index of Refraction | 1.579 |
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| InChIKey | VNRALGZMXHFBPG-UHFFFAOYSA-N |
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| SMILES | COc1ccc(C(Cl)=C(C=O)c2ccc(OC)cc2)cc1 |
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Safety Information
| Hazard Codes | Xi |
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| RIDADR | NONH for all modes of transport |
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| HS Code | 2913000090 |
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Customs
| HS Code | 2913000090 |
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| Summary | HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0% |
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Synonyms
| (Z)-3-chloro-2,3-bis(4-methoxyphenyl)propenal |
| 3-CHLORO-2,3-DI(4-METHOXYPHENYL)ACRYLALDEHYDE |
