Introduction：Basic information about CAS 537-09-7|Evernic Acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Evernic Acid |
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| CAS Number | 537-09-7 | Molecular Weight | 332.30500 |
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| Density | 1.391g/cm3 | Boiling Point | 531.8ºC at 760mmHg |
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| Molecular Formula | C17H16O7 | Melting Point | 166-167ºC |
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| MSDS | / | Flash Point | 194.6ºC |
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Names
| Name | 2-hydroxy-4-(2-hydroxy-4-methoxy-6-methylbenzoyl)oxy-6-methylbenzoic acid |
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| Synonym | More Synonyms |
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Evernic Acid BiologicalActivity
| Description | Evernic Acid is a secondary metabolite generated by lichens, including Ramalina, Evernia, and Hypogymnia, and several studies have described its anticancer, antifungal, and antimicrobial effects. Neuroprotective and anti-inflammatory effects[1]. |
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| Related Catalog | Research Areas >>Inflammation/ImmunologySignaling Pathways >>Anti-infection >>Bacterial |
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| Target | Fungal Metabolite |
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| References | [1]. Lee S, et al. Neuroprotective and Anti-Inflammatory Effects of Evernic Acid in an MPTP-Induced Parkinson's Disease Model. Int J Mol Sci. 2021;22(4):2098. Published 2021 Feb 20. |
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Chemical & Physical Properties
| Density | 1.391g/cm3 |
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| Boiling Point | 531.8ºC at 760mmHg |
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| Melting Point | 166-167ºC |
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| Molecular Formula | C17H16O7 |
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| Molecular Weight | 332.30500 |
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| Flash Point | 194.6ºC |
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| Exact Mass | 332.09000 |
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| PSA | 113.29000 |
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| LogP | 2.64060 |
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| Index of Refraction | 1.576 |
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| InChIKey | GODLCSLPZIBRMG-UHFFFAOYSA-N |
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| SMILES | COc1cc(C)c(C(=O)Oc2cc(C)c(C(=O)O)c(O)c2)c(O)c1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- GP4195000
- CHEMICAL NAME :
- 2,6-Cresotic acid, 4-methoxy-, 4-ester with 6-methyl-beta-resorcylate
- CAS REGISTRY NUMBER :
- 537-09-7
- BEILSTEIN REFERENCE NO. :
- 2227186
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C17-H16-O7
- MOLECULAR WEIGHT :
- 332.33
- WISWESSER LINE NOTATION :
- QR CQ E1 DVOVR BQ F1 DO1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 178 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01633
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Safety Information
Customs
| HS Code | 2918990090 |
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| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| EINECS 208-658-2 |
| Lecanoric acid methyl ether |
| Evernic acid,pruiss |
| Monomethylaether-p-diorsellinsaeure |
| 2-hydroxy-4-methoxy-6-methylbenzoic acid 4'-carboxy-3'-hydroxy-5'-methylphenyl ester |
| Evernic acid |
| Monomethylaether-lecanorsaeure |
