Introduction：Basic information about CAS 19083-00-2|gracillin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | gracillin |
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| CAS Number | 19083-00-2 | Molecular Weight | 885.043 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C45H72O17 | Melting Point | 290-293℃ (DEC.) |
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| MSDS | / | Flash Point | / |
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Names
| Name | Gracillin |
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| Synonym | More Synonyms |
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gracillin BiologicalActivity
| Description | Gracillin is a kind of steroidal saponin isolated from the root bark of wild yam Dioscorea nipponica with antitumor agent.Gracillin could induce cell cycle arrest, oxidative stress, and apoptosis in HL60 cells.[1] |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>CancerNatural Products >>Terpenoids and Glycosides |
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| References | [1]. Chen CR et al. Gracillin induces apoptosis in HL60 human leukemic cell line via oxidative stress and cell cycle arrest of G1. Pharmazie. 2015 Mar;70(3):199-204. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Melting Point | 290-293℃ (DEC.) |
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| Molecular Formula | C45H72O17 |
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| Molecular Weight | 885.043 |
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| Exact Mass | 884.476929 |
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| PSA | 255.91000 |
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| LogP | 4.41 |
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| Index of Refraction | 1.623 |
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| InChIKey | YQEMAEKYNNOCBY-IEMDQPGHSA-N |
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| SMILES | CC1CCC2(OC1)OC1CC3C4CC=C5CC(OC6OC(CO)C(O)C(OC7OC(CO)C(O)C(O)C7O)C6OC6OC(C)C(O)C(O)C6O)CCC5(C)C4CCC3(C)C1C2C |
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| Storage condition | -20°C |
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Safety Information
| Hazard Codes | Xn |
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| RIDADR | 3077.0 |
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| Hazard Class | 9.0 |
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| HS Code | 29329990 |
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Synonyms
| β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[β-D-glucopyranosyl-(1->3)]- |
| (3β,25R)-Spirost-5-en-3-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->3)]-β-D-glucopyranoside |
