Introduction：Basic information about CAS 708-53-2|2',3'-Dihydroxy-4'-methoxyacetophenone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2',3'-Dihydroxy-4'-methoxyacetophenone |
|---|
| CAS Number | 708-53-2 | Molecular Weight | 182.173 |
|---|
| Density | 1.3±0.1 g/cm3 | Boiling Point | 359.6±42.0 °C at 760 mmHg |
|---|
| Molecular Formula | C9H10O4 | Melting Point | 133ºC |
|---|
| MSDS | / | Flash Point | 147.7±21.4 °C |
|---|
Names
| Name | 1-(2,3-dihydroxy-4-methoxyphenyl)ethanone |
|---|
| Synonym | More Synonyms |
|---|
2',3'-Dihydroxy-4'-methoxyacetophenone BiologicalActivity
| Description | 2,3-Dihydroxy-4-methoxyacetophenone is a neuroprotective compound from Cynenchum paniculatum. 2,3-Dihydroxy-4-methoxyacetophenone improves cognitive function and may has the potential for the treatment of Alzheimer's disease research[1]. |
|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
|---|
| In Vitro | 2,3-Dihydroxy-4-methoxyacetophenone protects HT22 cells on glutamate induced cell-death in a dose-dependent manner (EC50=10.94 μM). 2,3-Dihydroxy-4-methoxyacetophenone inhibits [Ca2+] accumulation in HT22 cells and has antioxidantive activity[1]. |
|---|
| In Vivo | 2,3-dihydroxy-4-methoxyacetophenone (50mg/kg; po) improves the impairment of spatial memory induced by scopolamine[1]. |
|---|
| References | [1]. Jin Bae Weon, et al. The Ameliorating Effects of 2,3-dihydroxy-4-methoxyacetophenone on Scopolamine-Induced Memory Impairment in Mice and Its Neuroprotective Activity. Bioorg Med Chem Lett. 2013 Dec 15;23(24):6732-6. |
|---|
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|
| Boiling Point | 359.6±42.0 °C at 760 mmHg |
|---|
| Melting Point | 133ºC |
|---|
| Molecular Formula | C9H10O4 |
|---|
| Molecular Weight | 182.173 |
|---|
| Flash Point | 147.7±21.4 °C |
|---|
| Exact Mass | 182.057907 |
|---|
| PSA | 66.76000 |
|---|
| LogP | 1.81 |
|---|
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
|---|
| Index of Refraction | 1.573 |
|---|
| InChIKey | VCONERRCKOKCHE-UHFFFAOYSA-N |
|---|
| SMILES | COc1ccc(C(C)=O)c(O)c1O |
|---|
Safety Information
Customs
| HS Code | 2914509090 |
|---|
| Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
|---|
Synonyms
| 2,3-Dihydroxy-4-methoxy-acetophenon |
| Gallacetophenone-4'-methyl Ether |
| 2,3-dihydroxy-4-methoxyacetophenone |
| 1-acetyl-2,3-dihydroxy-4-methoxybenzene |
| Ethanone, 1-(2,3-dihydroxy-4-methoxyphenyl)- |
| MFCD00180772 |
| 1-(2,3-Dihydroxy-4-methoxyphenyl)ethanone |
| 1-(2,3-DIHYDROXY-4-METHOXYPHENYL)-ETHANONE |
