CAS 553-03-7|3,4-Dihydroquinolin-2(1H)-one
Introduction：Basic information about CAS 553-03-7|3,4-Dihydroquinolin-2(1H)-one, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 3,4-Dihydroquinolin-2(1H)-one | ||
|---|---|---|---|
| CAS Number | 553-03-7 | Molecular Weight | 147.174 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 328.1±31.0 °C at 760 mmHg |
| Molecular Formula | C9H9NO | Melting Point | 165-167ºC |
| MSDS | USA | Flash Point | 189.4±9.8 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 1,2,3,4-Tetrahydroquinolin-2-one |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 328.1±31.0 °C at 760 mmHg |
| Melting Point | 165-167ºC |
| Molecular Formula | C9H9NO |
| Molecular Weight | 147.174 |
| Flash Point | 189.4±9.8 °C |
| Exact Mass | 147.068420 |
| PSA | 29.10000 |
| LogP | 1.34 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.564 |
| InChIKey | TZOYXRMEFDYWDQ-UHFFFAOYSA-N |
| SMILES | O=C1CCc2ccccc2N1 |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H317-H319-H335 |
| Precautionary Statements | P261-P280-P305 + P351 + P338 |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R22;R36/37/38;R43 |
| Safety Phrases | S26-S36/37 |
| RIDADR | UN 2811 |
| WGK Germany | 2 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
Articles4
More Articles| Synthesis and biological evaluation of a novel sigma-1 receptor antagonist based on 3,4-dihydro-2(1H)-quinolinone scaffold as a potential analgesic. Eur. J. Med. Chem. 79 , 216-30, (2014) The synthesis and sigma-1 receptor (1R) antagonist activity of a new series of 3,4-dihydro-2(1H)-quinolinone derivatives are reported. The new compounds were evaluated in vitro in sigma-1 and sigma-2 ... | |
| Novel approach to 3,4-dihydro-2(1H)-quinolinone derivatives via cyclopropane ring expansion. Org. Lett. 11(5) , 1043-5, (2009) N-(1'-Alkoxy)cyclopropyl-2-haloanilines are transformed to 3,4-dihydro-2((1)H)-quinolinones via palladium-catalyzed cyclopropane ring expansion. The reaction tolerates a variety of functional groups s... | |
| Synthesis of 4-amino-3, 4-dihydro-2 (1H)-quinolinones via β-lactam intermediates on the solid-phase. Pei Y, et al. Tetrahedron Lett. 38(19) , 3349-52, (1997) |
Synonyms
| Dihydro-α-quinolone |
| 3,4-Dihydroquinolin-2(1H)-one |
| 3,4-dihydro-1H-quinolin-2-one |
| 2(1H)-Quinolinone, 3,4-dihydro- |
| MFCD00016722 |
| 3,4-Dihydro-2(1H)-quinolinone |
| T66 BMVT&J |
