CAS 120-87-6|9,10-dihydroxystearic acid

Introduction:Basic information about CAS 120-87-6|9,10-dihydroxystearic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name9,10-dihydroxystearic acid
CAS Number120-87-6Molecular Weight316.476
Density1.0±0.1 g/cm3Boiling Point481.6±25.0 °C at 760 mmHg
Molecular FormulaC18H36O4Melting Point92-94ºC
MSDS/Flash Point259.2±19.7 °C

Names

Name9,10-dihydroxystearic acid
SynonymMore Synonyms

9,10-dihydroxystearic acid BiologicalActivity

Description9,10-Dihydroxystearic acid is an oxidation product of oleic acid. 9,10-Dihydroxystearic acid can improve glucose tolerance and insulin sensitivity in KKAy mice[1].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease
In Vitro5-20 μmol/L 9,10-Dihydroxystearic acid (DHSA) does not activate PPAR-γ in CV-1 cells but 50-100 μmol/L DHSA activates PPAR-γ in a dose-dependent way. 9,10-Dihydroxystearic acid does not activate PPAR-α in CV-1 cells[1].
In Vivo9,10-Dihydroxystearic acid (DHSA; fed with high fat diet containing 4% DHSA; for 5-6 weeks) treatment improves glucose tolerance and insulin sensitivity in KKAy mice[1].
References

[1]. Xiaoming Yu, et al. Effects of 9,10-dihydroxysteatic acid on glucose metabolism in KKAy mice. Wei Sheng Yan Jiu. 2010 Jul;39(4):423-5.

Chemical & Physical Properties

Density1.0±0.1 g/cm3
Boiling Point481.6±25.0 °C at 760 mmHg
Melting Point92-94ºC
Molecular FormulaC18H36O4
Molecular Weight316.476
Flash Point259.2±19.7 °C
Exact Mass316.261353
PSA77.76000
LogP4.34
Vapour Pressure0.0±2.7 mmHg at 25°C
Index of Refraction1.481
InChIKeyVACHUYIREGFMSP-UHFFFAOYSA-N
SMILESCCCCCCCCC(O)C(O)CCCCCCCC(=O)O

Safety Information

Hazard CodesXn
HS Code2918199090

Customs

HS Code2918199090
Summary2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Synonyms

9 10-DIHYDROXYOCTADECANOIC ACID
Octadecanoic acid, 9,10-dihydroxy-
9,10-DIHYDROXYSTEARIC ACID
9,10-Dihydroxyoctadecanoic acid
9,10-Dihydroxystearate
EINECS 204-432-2
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