CAS 1132-26-9|2-Amino-2-methyl-3-phenylpropionic acid

Introduction:Basic information about CAS 1132-26-9|2-Amino-2-methyl-3-phenylpropionic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name2-Amino-2-methyl-3-phenylpropionic acid
CAS Number1132-26-9Molecular Weight179.21600
Density1.158 g/cm3Boiling Point306ºC at 760 mmHg
Molecular FormulaC10H13NO2Melting Point293-294ºC (dec.)
MSDSChineseUSAFlash Point138.9ºC

Names

Namealpha-Methyl-DL-phenylalanine
SynonymMore Synonyms

2-Amino-2-methyl-3-phenylpropionic acid BiologicalActivity

Descriptionα-Methyl-DL-phenylalanine is a phenylalanine derivative[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
In VitroAmino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-818.

Chemical & Physical Properties

Density1.158 g/cm3
Boiling Point306ºC at 760 mmHg
Melting Point293-294ºC (dec.)
Molecular FormulaC10H13NO2
Molecular Weight179.21600
Flash Point138.9ºC
Exact Mass179.09500
PSA63.32000
LogP1.73140
Vapour Pressure0.000345mmHg at 25°C
Index of Refraction1.561
InChIKeyHYOWVAAEQCNGLE-UHFFFAOYSA-N
SMILESCC(N)(Cc1ccccc1)C(=O)O
Storage conditionStore at RT.

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard CodesXn
Safety PhrasesS22-S24/25
RIDADRNONH for all modes of transport
WGK Germany3
HS Code2922499990

Customs

HS Code2922499990
SummaryHS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles26

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Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

Nat. Chem. Biol. 5 , 45-52, (2009)

Transporter-related nutrient sensors, called transceptors, mediate nutrient activation of signaling pathways through the plasma membrane. The mechanism of action of transporting and nontransporting tr...

Effects of dietary mixtures of amino acids on fetal growth and maternal and fetal amino acid pools in experimental maternal phenylketonuria.

Am. J. Clin. Nutr. 69(4) , 687-96, (1999)

Branched-chain amino acids have been reported to improve fetal brain development in a rat model in which maternal phenylketonuria (PKU) is induced by the inclusion of an inhibitor of phenylalanine hyd...

Inhibition of brain and liver 3-hydroxy-3-methylglutaryl-CoA reductase and mevalonate-5-pyrophosphate decarboxylase in experimental hyperphenylalaninemia.

Neurochem. Res. 13(6) , 551-5, (1988)

Experimental hyperphenylalaninemia has been induced in 5-day-old chicks by dietary treatments with phenylalanine and alpha-methylphenylalanine. An increase of nearly 8-fold in plasma Phe/Tyr ratio was...

Synonyms

MFCD00010512
2-amino-2-methyl-3-phenylpropanoic acid
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