CAS 119623-66-4|Diclofenac Epolamine

Introduction：Basic information about CAS 119623-66-4|Diclofenac Epolamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Diclofenac Epolamine BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Diclofenac Epolamine
CAS Number	119623-66-4	Molecular Weight	411.32
Density	/	Boiling Point	412ºC at 760mmHg
Molecular Formula	C₂₀H₂₄Cl₂N₂O₃	Melting Point	/
MSDS	/	Flash Point	203ºC

Names

Name	diclofenac epolamine
Synonym	More Synonyms

Diclofenac Epolamine BiologicalActivity

Description	Flector Patch (Diclofenac epolamine) is a non-steroidal anti-inflammatory drug (NSAID)[1]. Flector Patch is used for relieving arthritis Pain, acute Pain, osteoarthritis, and actinic Keratosis. Flector Patch has good skin absorption characteristics without local adverse reactions and allergies[2].
Related Catalog	Research Areas >>Inflammation/ImmunologySignaling Pathways >>Immunology/Inflammation >>COX
References	[1]. Del Río-Sancho S, et al. Topical delivery of diclofenac into and across equine skin from a novel liquid diclofenac epolamine formulation. J Vet Pharmacol Ther. 2016 Dec. 39(6):578-583. [2]. Fouad SA, Basalious EB, El-Nabarawi MA, Tayel SA. Microemulsion and poloxamer microemulsion-based gel for sustained transdermal delivery of diclofenac epolamine using in-skin drug depot: in vitro/in vivo evaluation. Int J Pharm. 2013 Sep 10;453(2):569-78.

Description

Flector Patch (Diclofenac epolamine) is a non-steroidal anti-inflammatory drug (NSAID)[1]. Flector Patch is used for relieving arthritis Pain, acute Pain, osteoarthritis, and actinic Keratosis. Flector Patch has good skin absorption characteristics without local adverse reactions and allergies[2].

Related Catalog

Research Areas >>Inflammation/ImmunologySignaling Pathways >>Immunology/Inflammation >>COX

References

[1]. Del Río-Sancho S, et al. Topical delivery of diclofenac into and across equine skin from a novel liquid diclofenac epolamine formulation. J Vet Pharmacol Ther. 2016 Dec. 39(6):578-583.

[2]. Fouad SA, Basalious EB, El-Nabarawi MA, Tayel SA. Microemulsion and poloxamer microemulsion-based gel for sustained transdermal delivery of diclofenac epolamine using in-skin drug depot: in vitro/in vivo evaluation. Int J Pharm. 2013 Sep 10;453(2):569-78.

Chemical & Physical Properties

Boiling Point	412ºC at 760mmHg
Molecular Formula	C₂₀H₂₄Cl₂N₂O₃
Molecular Weight	411.32
Flash Point	203ºC
PSA	60.77000
LogP	4.22370
Vapour Pressure	1.59E-07mmHg at 25°C
InChIKey	DCERVXIINVUMKU-UHFFFAOYSA-N
SMILES	O=C(O)Cc1ccccc1Nc1c(Cl)cccc1Cl.OCCN1CCCC1
Storage condition	-20℃

Safety Information

Hazard Codes	N

Synonyms

Benzeneacetic acid, 2-[(2,6-dichlorophenyl)methyl]-, compd. with 1-pyrrolidineethanol (1:1)

2-[2-(2,6-dichloroanilino)phenyl]acetic acid,2-pyrrolidin-1-ylethanol

UNII-X5F8EKL9ZG

Diclofenac hydroxyethylpyrrolidine

Diclofenac-N-(2-hydroxyethyl) pyrrolidine

[2-(2,6-Dichlorobenzyl)phenyl]acetic acid - 2-(1-pyrrolidinyl)ethanol (1:1)

DHEP plaster

Flector

Flector (TN)

DHEP

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