CAS 67375-30-8|α-cypermethrin

Introduction：Basic information about CAS 67375-30-8|α-cypermethrin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. α-cypermethrin BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
5. Safety Information
6. Articles55
7. Synonyms

Common Name	α-cypermethrin
CAS Number	67375-30-8	Molecular Weight	416.297
Density	1.3±0.1 g/cm3	Boiling Point	511.3±50.0 °C at 760 mmHg
Molecular Formula	C₂₂H₁₉Cl₂NO₃	Melting Point	78-81ºC
MSDS	ChineseUSA	Flash Point	263.0±30.1 °C
Symbol	GHS06, GHS08, GHS09	Signal Word	Danger

Names

Name	(1S)-cis-(αR)-cypermethrin
Synonym	More Synonyms

α-cypermethrin BiologicalActivity

Description	Alpha-Cypermethrin (FMC 45497; Fendona; WL 85871) is an effective insecticide against house flies[1].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
References	[1]. Abbas N, et al. Alpha-Cypermethrin Resistance in Musca domestica: Resistance Instability, Realized Heritability, Risk Assessment, and Insecticide Cross-Resistance. Insects. 2023 Feb 26;14(3):233.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	511.3±50.0 °C at 760 mmHg
Melting Point	78-81ºC
Molecular Formula	C₂₂H₁₉Cl₂NO₃
Molecular Weight	416.297
Flash Point	263.0±30.1 °C
Exact Mass	415.074188
PSA	118.64000
LogP	6.27
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.622
InChIKey	KAATUXNTWXVJKI-FDYSRKEFSA-N
SMILES	CC1(C)C(C=C(Cl)Cl)C1C(=O)OC(C#N)c1cccc(Oc2ccccc2)c1
Stability	Stable. Incompatible with strong oxidizing agents.

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GZ1251400

CHEMICAL NAME :: Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, cyano(3-phenoxyphenyl) methyl ester, (1-alpha(S*),3-alpha)-(+-)-

CAS REGISTRY NUMBER :: 67375-30-8

LAST UPDATED :: 199801

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C22-H19-Cl2-N-O3

MOLECULAR WEIGHT :: 416.32

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 79 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >1900 mg/m3/4H

TOXIC EFFECTS :: Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - changes in structure or function of salivary glands

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 336 mg/kg/28D-I

TOXIC EFFECTS :: Brain and Coverings - changes in brain weight Endocrine - changes in spleen weight Related to Chronic Data - changes in testicular weight

TYPE OF TEST :: Micronucleus test

MUTATION DATA

TEST SYSTEM :: Non-mammalian species

DOSE/DURATION :: 5 ppb

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 298,25,1992

Safety Information

Symbol	GHS06, GHS08, GHS09
Signal Word	Danger
Hazard Statements	H301-H335-H373-H410
Precautionary Statements	P273-P301 + P310 + P330-P391-P501
Hazard Codes	T:Toxic
Risk Phrases	R25;R37;R48/22;R50/53
Safety Phrases	S36/37/39-S45-S60-S61
RIDADR	UN 2811
WGK Germany	3
RTECS	GZ1250000
Packaging Group	III
Hazard Class	6.1(b)

Articles55

Choline partially prevents the impact of ethanol on the lipid raft dependent functions of l1 cell adhesion molecule.

Alcohol. Clin. Exp. Res. 38(11) , 2722-30, (2014)

Fetal alcohol spectrum disorder, the leading known cause of mental retardation, is caused by alcohol exposure during pregnancy. One mechanism of ethanol (EtOH) teratogenicity is the disruption of the ...

Development of a multi-residue method in a fetal matrix: analysis of meconium.

Anal. Bioanal. Chem 406(30) , 7785-97, (2014)

Meconium is the earliest stool of newborns. It is a complex matrix that reflects the degree of fetal exposure to environmental pollutants. To investigate exposure to xenobiotics, an analytical method ...

Atmospheric pressure gas chromatography-time-of-flight-mass spectrometry (APGC-ToF-MS) for the determination of regulated and emerging contaminants in aqueous samples after stir bar sorptive extraction (SBSE).

Anal. Chim. Acta 851 , 1-13, (2014)

This work presents the development, optimization and validation of a multi-residue method for the simultaneous determination of 102 contaminants, including fragrances, UV filters, repellents, endocrin...

Synonyms

Cyano(3-phenoxyphenyl)methyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate

3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid cyano(3-phenoxyphenyl)methyl ester

Cnn52

α-cypermethrin

(1S,3S)-(R)-Cyano(3-phenoxyphenyl)methyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate

rac-(R)-cyano(3-phenoxyphenyl)methyl (1S,3S)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate

UNII:1TR49121NP

(RS)-α-Cyano-3-phenoxybenzyl (1RS)-cis,trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate

(R)-cyano(3-phenoxyphenyl)methyl (1S,3S)-rel-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate

alphamethrin

alpha-cypermethrin

Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, cyano(3-phenoxyphenyl)methyl ester

(R)-Cyano(3-phenoxyphenyl)methyl (1S,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate - (S)-cyano(3-phenoxyphenyl)methyl (1R,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate (1:1)

(1S)-cis-(alphaR)-cypermethrin

Kefil Super

(RS)-α-cyano-3-phenoxybenzyl (1RS)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate

Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, cyano(3-phenoxyphenyl)methyl ester, (±)-

Cypermethrin

(RS)-α-cyano-3-phenoxybenzyl (1RS,3RS)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate

cypermethrin [ANSI]

Cyano(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate

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