Introduction：Basic information about CAS 67564-91-4|Fenpropimorph, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fenpropimorph |
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| CAS Number | 67564-91-4 | Molecular Weight | 303.48 |
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| Density | 0.928 g/cm3 | Boiling Point | 392.7ºC at 760 mmHg |
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| Molecular Formula | C20H33NO | Melting Point | 25°C |
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| MSDS | ChineseUSA | Flash Point | 115.6ºC |
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| Symbol |
GHS07, GHS08, GHS09 | Signal Word | Warning |
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Names
| Name | fenpropimorph |
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| Synonym | More Synonyms |
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Fenpropimorph BiologicalActivity
| Description | Fenpropimorph is a fungicide that inhibits the sterol pathway. Fenpropimorph inhibits δ8-δ7-sterol isomerase in yeast at low concentrations, with δ14-sterol reductase being blocked at higher levels, preventing the biosynthesis of ergosterol. Fenpropimorph also inhibits sterol synthesis in certain plants and mammalian cells[1][2][3]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Fungal |
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| References | [1]. Costet MF, et al. Ecdysteroid biosynthesis and embryonic development are disturbed in insects (Locusta migratoria) reared on plant diet (Triticum sativum) with a selectively modified sterol profile. Proc Natl Acad Sci U S A. 1987;84(3):643-647. [2]. Marcireau C, et al. In vivo effects of fenpropimorph on the yeast Saccharomyces cerevisiae and determination of the molecular basis of the antifungal property. Antimicrob Agents Chemother. 1990;34(6):989-993. [3]. Corio-Costet MF, et al. Inhibition by the fungicide fenpropimorph of cholesterol biosynthesis in 3T3 fibroblasts. Biochem J. 1988;256(3):829-834. |
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Chemical & Physical Properties
| Density | 0.928 g/cm3 |
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| Boiling Point | 392.7ºC at 760 mmHg |
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| Melting Point | 25°C |
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| Molecular Formula | C20H33NO |
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| Molecular Weight | 303.48 |
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| Flash Point | 115.6ºC |
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| Exact Mass | 303.25600 |
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| PSA | 12.47000 |
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| LogP | 4.20980 |
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| Index of Refraction | 1.49 |
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| InChIKey | RYAUSSKQMZRMAI-ALOPSCKCSA-N |
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| SMILES | CC(Cc1ccc(C(C)(C)C)cc1)CN1CC(C)OC(C)C1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- QE1940000
- CHEMICAL NAME :
- Morpholine, 2,6-dimethyl-4-(3-(4-(1,1-dimethylethyl)phenyl)-2-met hylpropyl)-, cis-
- CAS REGISTRY NUMBER :
- 67564-91-4
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C20-H33-N-O
- MOLECULAR WEIGHT :
- 303.54
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,379,1991
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2900 mg/m3/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,379,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,379,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5980 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,379,1991
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Safety Information
| Symbol |
GHS07, GHS08, GHS09 |
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| Signal Word | Warning |
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| Hazard Statements | H302-H315-H361d-H411 |
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| Precautionary Statements | P273-P281 |
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| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xn: Harmful;N: Dangerous for the environment; |
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| Risk Phrases | R22;R38;R51/53;R63 |
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| Safety Phrases | 36/37-46-61 |
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| RIDADR | UN 3082 |
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| RTECS | QE1940000 |
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Synonyms
| cis-4-<3-(4-tert-butylphenyl)-2-methylpropyl>-2,6-dimethylmorpholine |
| 4,10-dioxatricyclo[5.2.1.0<2,6>]decan-3,5-dione |
| Wln: T C555 A ao dvovtj |
| demethylcantharidin |
| (2R,6S)-rel-4-[3-[4-(1,1-dimethylethyl)phenyl]-2-methylpropyl]-2,6-dimethylmorpholine |
| rac-(2R,6S)-4-[(2Ξ)-3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine |
| 3,6-Endooxyphthalic anhydride,hexahydro |
| MFCD00144306 |
| rel-(2R,6S)-4-[3-[4-(1,1-dimethylethyl)phenyl]-2-methylpropyl]-2,6-dimethylmorpholine |
| hexahydro-4,7-epoxyisobenzofuran-1,3-dione |
| 7-oxabicyclo[2,2,1]heptane-2,3-dicarboxylic acid anhydride |
| cis-exo-hexahydro-4,7-epoxyisobenzofuran-1,3-dione |
| 4-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-2,6-dimethyl-morpholine |
| EINECS 266-719-9 |
| Fenpropimorph |
| Demehylcantharidin |
| cis-4-[(RS)-3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine |
| Hexahydro-3,6-epoxyphthalic anhydride |
| Nocantharidin |
| cis-4-[3-(p-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine |
| (exo)hexahydro-4,7-epoxyisobenzofuran-1,3-dione |
