CAS 53600-24-1|1-Hydroxyrutaecarpine

Introduction：Basic information about CAS 53600-24-1|1-Hydroxyrutaecarpine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 1-Hydroxyrutaecarpine BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	1-Hydroxyrutaecarpine
CAS Number	53600-24-1	Molecular Weight	303.31
Density	1.6±0.1 g/cm3	Boiling Point	601.7±65.0 °C at 760 mmHg
Molecular Formula	C₁₈H₁₃N₃O₂	Melting Point	/
MSDS	/	Flash Point	317.7±34.3 °C

Names

Name	1-Hydroxy-8,13-dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5( 7H)-one
Synonym	More Synonyms

1-Hydroxyrutaecarpine BiologicalActivity

Description	1-Hydroxyrutaecarpine (compound 1a) is a hydroxy-derivative of rutaecarpine. 1-Hydroxyrutaecarpine shows cytotoxicities with ED50s of 3.72, 7.44 µg/mL for P-388 and HT-29 cells, respectively. 1-Hydroxyrutaecarpine shows antiplatelet activity[1][2][3].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
References	[1]. Bruno Danieli; et al. 1-Hydroxyrutaecarpine from Euxylophora paraënsis. Phytochemistry, 1974 , 13(8), 1603–1606. [2]. Chen JJ, et al. New indolopyridoquinazoline, benzo[c]phenanthridines and cytotoxic constituents from Zanthoxylum integrifoliolum. Planta Med. 2005 May;71(5):470-5. [3]. Sheen WS, et al. Indolopyridoquinazoline alkaloids with antiplatelet aggregation activity from Zanthoxylum integrifoliolum. Planta Med. 1996 Apr;62(2):175-6.

Description

1-Hydroxyrutaecarpine (compound 1a) is a hydroxy-derivative of rutaecarpine. 1-Hydroxyrutaecarpine shows cytotoxicities with ED50s of 3.72, 7.44 µg/mL for P-388 and HT-29 cells, respectively. 1-Hydroxyrutaecarpine shows antiplatelet activity[1][2][3].

Related Catalog

Research Areas >>OthersSignaling Pathways >>Others >>Others

References

[1]. Bruno Danieli; et al. 1-Hydroxyrutaecarpine from Euxylophora paraënsis. Phytochemistry, 1974 , 13(8), 1603–1606.

[2]. Chen JJ, et al. New indolopyridoquinazoline, benzo[c]phenanthridines and cytotoxic constituents from Zanthoxylum integrifoliolum. Planta Med. 2005 May;71(5):470-5.

[3]. Sheen WS, et al. Indolopyridoquinazoline alkaloids with antiplatelet aggregation activity from Zanthoxylum integrifoliolum. Planta Med. 1996 Apr;62(2):175-6.

Chemical & Physical Properties

Density	1.6±0.1 g/cm3
Boiling Point	601.7±65.0 °C at 760 mmHg
Molecular Formula	C₁₈H₁₃N₃O₂
Molecular Weight	303.31
Flash Point	317.7±34.3 °C
Exact Mass	303.100769
PSA	70.91000
LogP	1.29
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.818
InChIKey	IBBYAIMGJMOBLQ-UHFFFAOYSA-N
SMILES	O=c1c2cccc(O)c2nc2n1CCc1c-2[nH]c2ccccc12

Synonyms

6-Methylmercapto-hexan-1-ol

7-thiaoctanol

1-hydroxyrutaecarpine

Indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one, 8,13-dihydro-1-hydroxy-

6-methylsulfanyl-hexan-1-ol

1-Hydroxy-8,13-dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one

1-Hydroxy-7-thiaoctane

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