Introduction：Basic information about CAS 86520-52-7|Azido-PEG3-alcohol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Azido-PEG3-alcohol |
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| CAS Number | 86520-52-7 | Molecular Weight | 175.18600 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C6H13N3O3 | Melting Point | / |
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| MSDS | / | Flash Point | -33℃ |
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| Symbol |
GHS02, GHS07 | Signal Word | Danger |
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Names
| Name | 2-[2-(2-Azidoethoxy)ethoxy]ethanol |
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| Synonym | More Synonyms |
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Azido-PEG3-alcohol BiologicalActivity
| Description | Azido-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228. |
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Chemical & Physical Properties
| Molecular Formula | C6H13N3O3 |
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| Molecular Weight | 175.18600 |
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| Flash Point | -33℃ |
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| Exact Mass | 175.09600 |
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| PSA | 88.44000 |
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| InChIKey | PMNIHDBMMDOUPD-UHFFFAOYSA-N |
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| SMILES | [N-]=[N+]=NCCOCCOCCO |
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| Storage condition | -20°C Freezer |
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Safety Information
| Symbol |
GHS02, GHS07 |
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| Signal Word | Danger |
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| Hazard Statements | H225-H315 |
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| Precautionary Statements | P210 |
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| Hazard Codes | F,Xi |
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| Risk Phrases | 11-38 |
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| Safety Phrases | 16 |
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| RIDADR | UN 2398 3 / PGII |
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| WGK Germany | 3 |
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| HS Code | 2929909090 |
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Customs
| HS Code | 2929909090 |
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| Summary | 2929909090 other compounds with other nitrogen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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Articles1
More Articles
| Synthesis of New Phospholipids Linked to Steroid-Hormone Derivatives Designed for Two-Dimensional Crystallization of Proteins Lebeau, L., et al. Helv. Chim. Acta 74 , 1697-1706, (1991)
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Synonyms
| 2-(2-(2-AZIDOETHOXY)ETHOXY)ETHANOL |
| N3-EEET-OH |
| 8-azido-3,6-dioxa-1-octanol |
| 1-Azido-8-hydroxy-3,6-dioxaoctane |
| Azido-PEG3 |
| 8-Azido-3,6-dioxaoctanol solution |
| azidotriethylene glycol |
| 8-Azido-3,6-dioxaoctanol |
| 8-azido-3,6-dioxaoctan-1-ol |
