Introduction：Basic information about CAS 42281-59-4|Oxilorphan, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Oxilorphan |
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| CAS Number | 42281-59-4 | Molecular Weight | 313.43400 |
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| Density | 1.27g/cm3 | Boiling Point | 495.4ºC at 760mmHg |
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| Molecular Formula | C20H27NO2 | Melting Point | / |
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| MSDS | / | Flash Point | 262.9ºC |
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Names
| Name | Oxilorphan |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.27g/cm3 |
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| Boiling Point | 495.4ºC at 760mmHg |
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| Molecular Formula | C20H27NO2 |
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| Molecular Weight | 313.43400 |
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| Flash Point | 262.9ºC |
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| Exact Mass | 313.20400 |
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| PSA | 43.70000 |
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| LogP | 2.91340 |
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| Index of Refraction | 1.653 |
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| InChIKey | STBZIDOIKQNFCQ-HSALFYBXSA-N |
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| SMILES | Oc1ccc2c(c1)C13CCCCC1(O)C(C2)N(CC1CC1)CC3 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- QC7800000
- CHEMICAL NAME :
- Morphinan-3,14-diol, 17-(cyclopropylmethyl)-
- CAS REGISTRY NUMBER :
- 42281-59-4
- LAST UPDATED :
- 199009
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C20-H27-N-O2
- MOLECULAR WEIGHT :
- 313.48
- WISWESSER LINE NOTATION :
- T6 G666/FQ 2AF Q FX ONT&TTJ AQ IQ O1- AL3TJ
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 14 ug/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Kidney, Ureter, Bladder - other changes
- REFERENCE :
- JCPCBR Journal of Clinical Pharmacology. (Hall Assoc., PO Box 482, Stamford, CT 06904) V.13- 1973- Volume(issue)/page/year: 16,183,1976
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 26 ug/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 2,746,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 315 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 193,23,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 32 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 193,23,1975
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Synonyms
| (L)-BC-2605 |
| Oxilorfano [INN-Spanish] |
| Levo-BC-2605 |
| Bristol laboratories BC 2605 |
| (-)-17-Cyclopropylmethylmorphinan-3,4-diol |
| 3,14-dihydroxy-N-cyclopropylmethylmorphinan |
| EINECS 255-749-8 |
