Introduction：Basic information about CAS 127785-64-2|Basifungin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Basifungin |
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| CAS Number | 127785-64-2 | Molecular Weight | 1101.42000 |
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| Density | 1.19g/cm3 | Boiling Point | 1229.1ºC at 760 mmHg |
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| Molecular Formula | C60H92N8O11 | Melting Point | / |
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| MSDS | / | Flash Point | 697.1ºC |
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Names
| Name | aureobasidin A |
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| Synonym | More Synonyms |
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Basifungin BiologicalActivity
| Description | Aureobasidin A (Basifungin), a cyclic depsipetide, is an antifungal antibiotic. Aureobasidin A (Basifungin) A is an inhibitor of the inositolphosphorylceramide synthase AUR1[1][2]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>FungalResearch Areas >>Inflammation/Immunology |
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| In Vitro | Aureobasidin A arrests growth of yeast cells through both ceramide intoxication and deprivation of essential inositolphosphorylceramides[2]. |
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| References | [1]. K Ikai, et al. Structure of aureobasidin A. J Antibiot (Tokyo). 1991 Sep;44(9):925-33. [2]. Vanessa Cerantola, et al. Aureobasidin A arrests growth of yeast cells through both ceramide intoxication and deprivation of essential inositolphosphorylceramides. Mol Microbiol. 2009 Mar;71(6):1523-37. [3]. K Kino, et al. Aureobasidin A, an antifungal cyclic depsipeptide antibiotic, is a substrate for both human MDR1 and MDR2/P-glycoproteins. FEBS Lett. 1996 Dec 9;399(1-2):29-32. |
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Chemical & Physical Properties
| Density | 1.19g/cm3 |
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| Boiling Point | 1229.1ºC at 760 mmHg |
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| Molecular Formula | C60H92N8O11 |
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| Molecular Weight | 1101.42000 |
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| Flash Point | 697.1ºC |
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| Exact Mass | 1100.69000 |
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| PSA | 245.85000 |
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| LogP | 4.88900 |
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| Vapour Pressure | 0mmHg at 25°C |
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| Index of Refraction | 1.574 |
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| InChIKey | RLMLFADXHJLPSQ-UHFFFAOYSA-N |
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| SMILES | CCC(C)C1NC(=O)C2CCCN2C(=O)C(Cc2ccccc2)N(C)C(=O)C(Cc2ccccc2)NC(=O)C(C(C)C)N(C)C(=O)C(C(C)CC)OC(=O)C(C(C)(C)O)N(C)C(=O)C(CC(C)C)NC(=O)C(C(C)C)N(C)C1=O |
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Synonyms
