Introduction：Basic information about CAS 42863-81-0|7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydropyrido[3,2-e][1,4]diazepin-2-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydropyrido[3,2-e][1,4]diazepin-2-one |
|---|
| CAS Number | 42863-81-0 | Molecular Weight | 322.14600 |
|---|
| Density | 1.61g/cm3 | Boiling Point | 563.9ºC at 760mmHg |
|---|
| Molecular Formula | C14H9Cl2N3O2 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 294.8ºC |
|---|
Names
| Name | 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydropyrido[3,2-e][1,4]diazepin-2-one |
|---|
| Synonym | More Synonyms |
|---|
BiologicalActivity
| Description | Lopirazepam is a potent small molecule GABAA receptor agonist, which can be used to treat anxiety disorders, insomnia, epilepsy and other diseases. |
|---|
| References | 1. Fabian A,et al. Veränderungen der Dauer der Schlafzyklen unter Flurazepam und Lopirazepam [Changes in the length of sleep cycles during administration of flurazepam and lopirazepam]. EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1984 Sep;15(3):151-8. German. |
|---|
Chemical & Physical Properties
| Density | 1.61g/cm3 |
|---|
| Boiling Point | 563.9ºC at 760mmHg |
|---|
| Molecular Formula | C14H9Cl2N3O2 |
|---|
| Molecular Weight | 322.14600 |
|---|
| Flash Point | 294.8ºC |
|---|
| Exact Mass | 321.00700 |
|---|
| PSA | 78.07000 |
|---|
| LogP | 2.01700 |
|---|
| Index of Refraction | 1.726 |
|---|
| InChIKey | JEJOFYTVMFVKQA-UHFFFAOYSA-N |
|---|
| SMILES | O=C1Nc2ccc(Cl)nc2C(c2ccccc2Cl)=NC1O |
|---|
Synonyms
| Lopirazepam [INN] |
| 2H-Pyrido(3,2-e)-1,4-diazepin-2-one,1,3-dihydro-7-chloro-5-(2-chlorophenyl)-3-hydroxy |
| 3-Hydroxy-5-o-chlorophenyl-6-aza-7-chloro-1,2-dihydro-3H-1,4-benzodiazepinone |
| EINECS 255-974-1 |
| Lopirazepamum [INN-Latin] |
| 2H-Pyrido(3,2-e)-1,4-diazepin-2-one,7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy |
| 7-chloro-5-(2-chloro-phenyl)-3-hydroxy-1,3-dihydro-pyrido[3,2-e][1,4]diazepin-2-one |
| 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2h-pyrido[3,2-e][1,4]diazepin-2-one |
| 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-pyrido(3,2-e)-1,4-diazepin-2-one |
| Lopirazepam |
