CAS 851371-22-7|(4'-Furan-2-yl-[4,5']bipyrimidinyl-2'-yl)-pyridin-3-yl-amine

Introduction：Basic information about CAS 851371-22-7|(4'-Furan-2-yl-[4,5']bipyrimidinyl-2'-yl)-pyridin-3-yl-amine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	(4'-Furan-2-yl-[4,5']bipyrimidinyl-2'-yl)-pyridin-3-yl-amine
CAS Number	851371-22-7	Molecular Weight	316.32
Density	/	Boiling Point	/
Molecular Formula	C₁₇H₁₂N₆O	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	4-(furan-2-yl)-N-pyridin-3-yl-5-pyrimidin-4-ylpyrimidin-2-amine
Synonym	More Synonyms

BiologicalActivity

Description	LAS38096 is a potent, selective, and efficacious A2B Adenosine Receptor antagonist, with a Ki of 17 nM[1].
Related Catalog	Research Areas >>OthersSignaling Pathways >>GPCR/G Protein >>Adenosine Receptor
Target	A2B:17 nM (Ki) A1:>1000 nM (Ki) A2A:>2500 nM (Ki) A3:>1000 nM (Ki)
References	[1]. Bernat Vidal, et al. Discovery and characterization of 4'-(2-furyl)-N-pyridin-3-yl-4,5'-bipyrimidin-2'-amine (LAS38096), a potent, selective, and efficacious A2B adenosine receptor antagonist. J Med Chem. 2007 May 31;50(11):2732-6.

Chemical & Physical Properties

Molecular Formula	C₁₇H₁₂N₆O
Molecular Weight	316.32
Exact Mass	316.10700
PSA	89.62000
LogP	3.40520

Safety Information

HS Code	2934999090

Customs

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

Kinome_3729

[4,5'-Bipyrimidin]-2'-amine,4'-(2-furanyl)-N-3-pyridinyl

4'-(Furan-2-yl)-N-(pyridin-3-yl)-[4,5'-bipyrimidin]-2'-amine

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