Introduction：Basic information about CAS 15180-02-6|amfonelic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | amfonelic acid |
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| CAS Number | 15180-02-6 | Molecular Weight | 308.33 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 499.3±45.0 °C at 760 mmHg |
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| Molecular Formula | C18H16N2O3 | Melting Point | / |
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| MSDS | / | Flash Point | 255.8±28.7 °C |
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Names
| Name | 7-benzyl-1-ethyl-4-oxo-1,8-naphthyridine-3-carboxylic acid |
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| Synonym | More Synonyms |
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amfonelic acid BiologicalActivity
| Description | Amfonelic acid (WIN-25978) is a highly selective dopamine reuptake inhibitor. Amfonelic acid interferes with the in vitro neuronal uptake of norepinephrine in the iris of rats, but does not alter the concentrations of norepinephrine or dopamine in the whole mouse brain. Amfonelic acid can be used as a pharmacological tool to study the brain reward system, dopamine pathway and dopamine transporter[1]. |
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| Related Catalog | Research Areas >>Neurological Disease |
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| References | [1]. Aceto MD, et al. Pharmacologic properties and mechanism of action of amfonelic acid. Eur J Pharmacol. 1970;10(3):344-54. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 499.3±45.0 °C at 760 mmHg |
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| Molecular Formula | C18H16N2O3 |
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| Molecular Weight | 308.33 |
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| Flash Point | 255.8±28.7 °C |
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| Exact Mass | 308.116089 |
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| PSA | 72.19000 |
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| LogP | 2.72 |
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| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
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| Index of Refraction | 1.630 |
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| InChIKey | WHHHJDGNBVQNAU-UHFFFAOYSA-N |
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| SMILES | CCn1cc(C(=O)O)c(=O)c2ccc(Cc3ccccc3)nc21 |
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2933990090 |
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Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-1,4-dihydro-4-oxo-7-(phenylmethyl)- |
| amfonelic acid |
| 7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid |
| Amfonelinsaeure |
| 7-Benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridin-3-carbonsaeure |
| 7-Benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid |
| 1-Ethyl-1,4-dihydro-4-oxo-7-(phenylmethyl)-1,8-naphthyridine-3-carboxylic Acid |
