CAS 5405-53-8|2,7-dinitro-9H-fluorene
Introduction：Basic information about CAS 5405-53-8|2,7-dinitro-9H-fluorene, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2,7-dinitro-9H-fluorene | ||
|---|---|---|---|
| CAS Number | 5405-53-8 | Molecular Weight | 256.214 |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 451.5±38.0 °C at 760 mmHg |
| Molecular Formula | C13H8N2O4 | Melting Point | 330-334°C |
| MSDS | ChineseUSA | Flash Point | 229.9±19.6 °C |
| Symbol | GHS08 | Signal Word | Warning |
Names
| Name | 2,7-Dinitrofluorene |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 451.5±38.0 °C at 760 mmHg |
| Melting Point | 330-334°C |
| Molecular Formula | C13H8N2O4 |
| Molecular Weight | 256.214 |
| Flash Point | 229.9±19.6 °C |
| Exact Mass | 256.048401 |
| PSA | 91.64000 |
| LogP | 3.62 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.705 |
| InChIKey | IHZCVUBSTYOFSJ-UHFFFAOYSA-N |
| SMILES | O=[N+]([O-])c1ccc2c(c1)Cc1cc([N+](=O)[O-])ccc1-2 |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2700 mg/kg/17W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors
MUTATION DATA - TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Rodent - mouse Liver
- DOSE/DURATION :
- 2500 ug/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 190,159,1987
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Rodent - mouse Liver
- DOSE/DURATION :
- 2500 ug/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 190,159,1987
Safety Information
| Symbol | GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H351 |
| Precautionary Statements | P281 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R40 |
| Safety Phrases | S7-S22-S36/37/39-S45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | LL7175000 |
| HS Code | 2904209090 |
Customs
| HS Code | 2904209090 |
|---|---|
| Summary | 2904209090 derivatives containing only nitro or only nitroso groups。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
Articles6
More Articles| Voltammetric detection of damage to DNA caused by nitro derivatives of fluorene using an electrochemical DNA biosensor. Anal. Bioanal. Chem 397(1) , 233-41, (2010) An electrochemical DNA biosensor based on the screen printed carbon paste electrode (SPCPE) with an immobilized layer of calf thymus double-stranded DNA has been used for in vitro investigation of the... | |
| Preneoplastic lesions and DNA adduct formation of the airborne genotoxic agents 2-nitrofluorene and 2,7-dinitrofluorene. Carcinogenesis 14(12) , 2627-32, (1993) The urinary mutagenicity (unconjugated forms) after administration of 2,7-dinitrofluorene (2,7-dNF) orally or i.p. was lower compared to 2-nitrofluorene (NF) administration. When partial hepatectomy (... | |
| Reductions of nitro and 9-Oxo groups of environmental nitrofluorenes by the rat mammary gland in vitro. Chem. Res. Toxicol. 13(8) , 793-800, (2000) Nitrofluorenes and C-9-oxidized nitrofluorenes are widespread environmental genotoxins which may be relevant for breast cancer on the basis of their carcinogenicities, particularly of 2, 7-dinitrofluo... |
Synonyms
| 9H-Fluorene, 2,7-dinitro- |
| EINECS 226-457-8 |
| 2,7-dinitro-9H-fluorene |
| MFCD00001121 |
