CAS 510-30-5|Echinocystic acid

Introduction：Basic information about CAS 510-30-5|Echinocystic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Echinocystic acid BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Echinocystic acid
CAS Number	510-30-5	Molecular Weight	472.700
Density	1.1±0.1 g/cm3	Boiling Point	585.0±50.0 °C at 760 mmHg
Molecular Formula	C₃₀H₄₈O₄	Melting Point	299-300ºC
MSDS	/	Flash Point	321.6±26.6 °C

Names

Name	echinocystic acid
Synonym	More Synonyms

Echinocystic acid BiologicalActivity

Description	Echinocystic acid a pentacyclic triterpene isolated from the fruits of Gleditsia sinensis Lam, has potent antioxidant, anti-inflammatory and anti-tumor properties. In vitro: Echinocystic acid (EA) inhibit the formation of osteoclast. EA inhibit RANKL-induced NF-κB activation and ERK phosphorylation in BMMs. [1] EA inhibit IL-1β-induced inflammation in chondrocytes. [2]In vivo: Echinocystic acid reduces reserpine-induced pain/depression dyad in mice. [3]
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/ImmunologyNatural Products >>Terpenoids and Glycosides
References	[1]. Yang JH et al. Echinocystic acid inhibits RANKL-induced osteoclastogenesis by regulating NF-κB and ERK signaling pathways. Biochem Biophys Res Commun. 2016 Sep 2;477(4):673-7. [2]. Ma Z et al. Echinocystic Acid Inhibits IL-1β-Induced COX-2 and iNOS Expression in Human Osteoarthritis Chondrocytes. Inflammation. 2016 Apr;39(2):543-9. [3]. Li S et al. Echinocystic acid reduces reserpine-induced pain/depression dyad in mice. Metab Brain Dis. 2016 Apr;31(2):455-63.

Description

Echinocystic acid a pentacyclic triterpene isolated from the fruits of Gleditsia sinensis Lam, has potent antioxidant, anti-inflammatory and anti-tumor properties. In vitro: Echinocystic acid (EA) inhibit the formation of osteoclast. EA inhibit RANKL-induced NF-κB activation and ERK phosphorylation in BMMs. [1] EA inhibit IL-1β-induced inflammation in chondrocytes. [2]In vivo: Echinocystic acid reduces reserpine-induced pain/depression dyad in mice. [3]

Related Catalog

Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/ImmunologyNatural Products >>Terpenoids and Glycosides

References

[1]. Yang JH et al. Echinocystic acid inhibits RANKL-induced osteoclastogenesis by regulating NF-κB and ERK signaling pathways. Biochem Biophys Res Commun. 2016 Sep 2;477(4):673-7.

[2]. Ma Z et al. Echinocystic Acid Inhibits IL-1β-Induced COX-2 and iNOS Expression in Human Osteoarthritis Chondrocytes. Inflammation. 2016 Apr;39(2):543-9.

[3]. Li S et al. Echinocystic acid reduces reserpine-induced pain/depression dyad in mice. Metab Brain Dis. 2016 Apr;31(2):455-63.

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	585.0±50.0 °C at 760 mmHg
Melting Point	299-300ºC
Molecular Formula	C₃₀H₄₈O₄
Molecular Weight	472.700
Flash Point	321.6±26.6 °C
Exact Mass	472.355255
PSA	77.76000
LogP	7.58
Vapour Pressure	0.0±3.7 mmHg at 25°C
Index of Refraction	1.568
InChIKey	YKOPWPOFWMYZJZ-HJENMKQUSA-N
SMILES	CC1(C)CCC2(C(=O)O)C(O)CC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C2C1
Storage condition	2-8C

Synonyms

(4aR,5R,6aS,6bR,8aR,10S,12aR,12bR,14bS)-5,10-Dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydro-4a(2H)-picenecarboxylic acid

Echicystic acid

(3β,16α)-3,16-Dihydroxyolean-12-en-28-oic acid

Albizziagenin

Echinocystsaeure

3-B,16-A-DIHYDROXYOLEAN-12-EN-28-OIC ACID

echinaystic acid

Olean-12-en-28-oic acid, 3,16-dihydroxy-, (3β,16α)-

Echinocystic

Recommended......