CAS 26652-09-5|ritodrine

Introduction：Basic information about CAS 26652-09-5|ritodrine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. ritodrine BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Synonyms

Common Name	ritodrine
CAS Number	26652-09-5	Molecular Weight	287.35400
Density	1.213g/cm3	Boiling Point	512.3ºC at 760mmHg
Molecular Formula	C₁₇H₂₁NO₃	Melting Point	/
MSDS	/	Flash Point	175.6ºC

Names

Name	4-[2-[[(1R,2S)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]phenol
Synonym	More Synonyms

ritodrine BiologicalActivity

Description	Ritodrine (DU21220) is a β-adrenergic agonist, also an effective uterine relaxant, can be used for researching arrest premature labor[1][2].
Related Catalog	Research Areas >>EndocrinologySignaling Pathways >>GPCR/G Protein >>Adrenergic Receptor
References	[1]. Spellacy WN, et al. Treatment of premature labor with ritodrine: a randomized controlled study. Obstet Gynecol. 1979 Aug;54(2):220-3. [2]. Canadian Preterm Labor Investigators Group. Treatment of preterm labor with the beta-adrenergic agonist ritodrine. N Engl J Med. 1992 Jul 30;327(5):308-12.

Description

Ritodrine (DU21220) is a β-adrenergic agonist, also an effective uterine relaxant, can be used for researching arrest premature labor[1][2].

Related Catalog

Research Areas >>EndocrinologySignaling Pathways >>GPCR/G Protein >>Adrenergic Receptor

References

[1]. Spellacy WN, et al. Treatment of premature labor with ritodrine: a randomized controlled study. Obstet Gynecol. 1979 Aug;54(2):220-3.

[2]. Canadian Preterm Labor Investigators Group. Treatment of preterm labor with the beta-adrenergic agonist ritodrine. N Engl J Med. 1992 Jul 30;327(5):308-12.

Chemical & Physical Properties

Density	1.213g/cm3
Boiling Point	512.3ºC at 760mmHg
Molecular Formula	C₁₇H₂₁NO₃
Molecular Weight	287.35400
Flash Point	175.6ºC
Exact Mass	287.15200
PSA	72.72000
LogP	2.74290
Vapour Pressure	2.55E-11mmHg at 25°C
Index of Refraction	1.618
InChIKey	IOVGROKTTNBUGK-SJKOYZFVSA-N
SMILES	CC(NCCc1ccc(O)cc1)C(O)c1ccc(O)cc1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DA4797050

CHEMICAL NAME :: Benzenemethanol, 4-hydroxy-alpha-(1-((2-(4-hydroxyphenyl)ethyl)amino)e thyl)-, (R*,S*)-

CAS REGISTRY NUMBER :: 26652-09-5

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C17-H21-N-O3

MOLECULAR WEIGHT :: 287.39

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Multiple routes

DOSE :: 21040 ug/kg

SEX/DURATION :: female 10-35 week(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system

REFERENCE :: EOGRAL European Journal of Obstetrics, Gynecology and Reproductive Biology. (Elsevier Science Pub. BV, POB 211, 1000 AE Amsterdam, Netherlands) V.3- 1973- Volume(issue)/page/year: 59,137,1995

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

DOSE :: 3000 ug/kg

SEX/DURATION :: female 20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - other effects

REFERENCE :: BMMBES Biochemical Medicine and Metabolic Biology. (Academic Press, Inc., Journal Customer Service, POB 6250, Duluth, MN 55802-0250) V.35- 1986- Volume(issue)/page/year: 52,128,1994

Synonyms

ritodrine

Yutopar S.R

Ritodrina

Utopar

Ritodrinium

Yutopar

Prepar

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