CAS 110-44-1|Sorbic acid
Introduction：Basic information about CAS 110-44-1|Sorbic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Sorbic acid | ||
|---|---|---|---|
| CAS Number | 110-44-1 | Molecular Weight | 112.127 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 233.0±9.0 °C at 760 mmHg |
| Molecular Formula | C6H8O2 | Melting Point | 132-135 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 139.9±9.6 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | (2E,4E)-hexa-2,4-dienoic acid |
|---|---|
| Synonym | More Synonyms |
Sorbic acid BiologicalActivity
| Description | Sorbic acid, isolated from Sorbus aucuparia, is a naturally occurring, highly efficient, and nonpoisonous food preservative. Sorbic acid generally is an effective inhibitor of most molds and yeasts and some bacteria[1]. |
|---|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>FungalSignaling Pathways >>Anti-infection >>Bacterial |
| References | [1]. Liewen MB, et al. Growth and Inhibition of Microorganisms in the Presence of Sorbic Acid: A Review. J Food Prot. 1985 Apr;48(4):364-375. |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 233.0±9.0 °C at 760 mmHg |
| Melting Point | 132-135 °C(lit.) |
| Molecular Formula | C6H8O2 |
| Molecular Weight | 112.127 |
| Flash Point | 139.9±9.6 °C |
| Exact Mass | 112.052429 |
| PSA | 37.30000 |
| LogP | 1.35 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.488 |
| InChIKey | WSWCOQWTEOXDQX-MQQKCMAXSA-N |
| SMILES | CC=CC=CC(=O)O |
| Stability | Stability Material saturated with this acid may ignite spontaneously. Incompatible with strong oxidizing agents. May be light sensitive. |
| Water Solubility | 1.6 g/L (20 ºC) |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Human - man
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7360 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2820 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2820 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1040 mg/kg/65W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
MUTATION DATA - TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 1050 mg/L
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 22,501,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81510 No. of Facilities: 583 (estimated) No. of Industries: 6 No. of Occupations: 11 No. of Employees: 4662 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81510 No. of Facilities: 4412 (estimated) No. of Industries: 45 No. of Occupations: 59 No. of Employees: 69243 (estimated) No. of Female Employees: 21637 (estimated)
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 1050 mg/L
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 22,501,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81510 No. of Facilities: 583 (estimated) No. of Industries: 6 No. of Occupations: 11 No. of Employees: 4662 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81510 No. of Facilities: 4412 (estimated) No. of Industries: 45 No. of Occupations: 59 No. of Employees: 69243 (estimated) No. of Female Employees: 21637 (estimated)
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/38 |
| Safety Phrases | S26-S36-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 1 |
| RTECS | WG2100000 |
| HS Code | 2916190090 |
Customs
| HS Code | 2916190090 |
|---|---|
| Summary | 2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0% |
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| Simultaneous determination of eleven preservatives in cosmetics by micellar electrokinetic chromatography. J. AOAC Int. 95(4) , 1069-73, (2012) A new method for the simultaneous quantitation of 11 preservatives-imidazolidinyl urea, benzyl alcohol, dehydroacetic acid, sorbic acid, phenoxyethanol, benzoic acid, salicylic acid, and four parabens... | |
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Synonyms
| Sorbistat |
| 2,4-Hexadienoic acid |
| EINECS 203-768-7 |
| 2,4-Hexadienoic acid, (E,E)- |
| trans-trans-2,4-Hexadienoic acid |
| MFCD00002703 |
| sorbic |
| (2E,4E)-hexa-2,4-dienoic acid |
| sorbinic acid |
| trans,trans-sorbic acid |
| all-E-sorbic acid |
| Sorbic acid |
| trans,trans-2,4-hexadienoic acid |
| (2E,4E)hexa-2,4-dienoic acid |
| (E,E)-2,4-Hexadienoic acid |
| Sorbinsure |
| hexa-2 |
| (E,E)-hexa-2,4-dienoic acid |
| (2E,4E)-2,4-Hexadienoic acid |
| C6:2n-2,4 |
| hexadienoic acid |
| 2,4-Hexadienoic acid, (2E,4E)- |
| Panosorb |
| FEMA 3921 |
