CAS 157606-25-2|Cecropin A (1-7)-Melittin A (2-9) amide trifluoroacetate salt

Introduction：Basic information about CAS 157606-25-2|Cecropin A (1-7)-Melittin A (2-9) amide trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Cecropin A (1-7)-Melittin A (2-9) amide trifluoroacetate salt
CAS Number	157606-25-2	Molecular Weight	1770.30000
Density	/	Boiling Point	/
Molecular Formula	C₈₉H₁₅₂N₂₂O₁₅	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	cecropin a (1-7)-melittin a (2-9) amide
Synonym	More Synonyms

BiologicalActivity

Description	Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial activity, without the adverse hemolytic properties of bee venom peptides[1].
Related Catalog	Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial
In Vitro	Cecropin A (1-7)-Melittin A (2-9) (0-64 mg/L, 48 h) 作用于E. coli ATCC 25922, Staphylococcus aureus ATCC 29213, B. fragilis NCTC 9343 和 C. pefringens ATCC 13124 的 MIC 值分别为 8 mg/L, 32 mg/L, 8 mg/L and 64 mg/L[1]。
References	[1]. Charlotta Edlund, et al. Antianaerobic activity of a cecropin---melittin peptide. Clin Microbiol Infect. 1998 Apr;4(4):181-185.

Chemical & Physical Properties

Molecular Formula	C₈₉H₁₅₂N₂₂O₁₅
Molecular Weight	1770.30000
Exact Mass	1769.18000
PSA	622.40000
LogP	10.72030
InChIKey	WMTUWZOBAVPERW-VZYQMWHSSA-N
SMILES	CCC(C)C(NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(Cc1ccccc1)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(N)CCCCN)C(=O)NCC(=O)NC(C)C(=O)NC(C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(C(=O)NC(CC(C)C)C(N)=O)C(C)C)C(C)C

Synonyms

H-LYS-TRP-LYS-LEU-PHE-LYS-LYS-ILE-GLY-ALA-VAL-LEU-LYS-VAL-LEU-NH2

CECROPIN A-MELITTIN HYBRID PEPTIDE

LYS-TRP-LYS-LEU-PHE-LYS-LYS-ILE-GLY-ALA-VAL-LEU-LYS-VAL-LEU-NH2

KWKLFKKIGAVLKVL-NH2

KWKLFKKIGAVLKVL-amide

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