CAS 1570-64-5|4-Chloro-2-methylphenol

Introduction：Basic information about CAS 1570-64-5|4-Chloro-2-methylphenol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Safety Information
5. Customs
6. Articles18
7. Synonyms

Common Name	4-Chloro-2-methylphenol
CAS Number	1570-64-5	Molecular Weight	142.583
Density	1.2±0.1 g/cm3	Boiling Point	225.3±20.0 °C at 760 mmHg
Molecular Formula	C₇H₇ClO	Melting Point	43-46 °C(lit.)
MSDS	ChineseUSA	Flash Point	90.1±21.8 °C
Symbol	GHS05, GHS06, GHS09	Signal Word	Danger

Names

Name	4-chloro-2-methylphenol
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	225.3±20.0 °C at 760 mmHg
Melting Point	43-46 °C(lit.)
Molecular Formula	C₇H₇ClO
Molecular Weight	142.583
Flash Point	90.1±21.8 °C
Exact Mass	142.018539
PSA	20.23000
LogP	2.89
Vapour Pressure	0.1±0.5 mmHg at 25°C
Index of Refraction	1.566
InChIKey	RHPUJHQBPORFGV-UHFFFAOYSA-N
SMILES	Cc1cc(Cl)ccc1O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GO7120000

CHEMICAL NAME :: o-Cresol, 4-chloro-

CAS REGISTRY NUMBER :: 1570-64-5

BEILSTEIN REFERENCE NO. :: 1906684

LAST UPDATED :: 199710

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C7-H7-Cl-O

MOLECULAR WEIGHT :: 142.59

WISWESSER LINE NOTATION :: QR DG B1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 100 ug/plate

REFERENCE :: TECSDY Toxicological and Environmental Chemistry. (Gordon & Breach Science Pub. Inc., 1 Park Ave., New York, NY 10016) V.3(3/4)- 1981- Volume(issue)/page/year: 14,143,1987

Safety Information

Symbol	GHS05, GHS06, GHS09
Signal Word	Danger
Hazard Statements	H314-H331-H400
Precautionary Statements	P261-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338-P403 + P233
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T:Toxic;C:Corrosive;N:Dangerousfortheenvironment;
Risk Phrases	R23;R35;R50
Safety Phrases	S26-S36/37/39-S45-S61
RIDADR	UN 3437 6.1/PG 2
WGK Germany	2
RTECS	GO7120000
Packaging Group	II
Hazard Class	6.1
HS Code	2908199090

Customs

HS Code	2908199090
Summary	HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%

Articles18

Chromatographic evaluation and QSAR optimization for benzoic acid analogues against carbonic anhydrase III.

J. Enzyme Inhib. Med. Chem. 30 , 420-9, (2015)

An HPLC-size exclusion method was developed as an assay method to evaluate the binding of tested compounds with carbonic anhydrase III (CAIII) enzyme. Inhibition of CAIII by a group of benzoic acid an...

Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.

J. Med. Chem. 48 , 5666-74, (2005)

We investigated the influence of induced fit of the androgen receptor binding pocket on free energies of ligand binding. On the basis of a novel alignment procedure using flexible docking, molecular d...

The effect of structure and a secondary carbon source on the microbial degradation of chlorophenoxy acids.

Chemosphere 79(11) , 1084-8, (2010)

Pseudomonas putida, Aspergillus niger, Bacillus subtilis, Pseudomonas fluorescens, Sphingomonas herbicidovorans and Rhodococcus rhodochrous growing on glucose in a medium containing one of three chlor...

Synonyms

Phenol, 4-chloro-2-methyl-

4-chlorocresol

p-Chloro-o-cresol

4-Chlor-2-methylbenzolol

o-Cresol,4-chloro

2-METHYL-4-CHLOROPHENOL

4-Chloro-2-cresol

Phenol,4-chloro-2-methyl

4-Chloro-2-methylphenol

4-chloro-2-methyl phenol

EINECS 216-381-3

4-chloro-o-cresol

para-chloro-o-cresol

MFCD00002321

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