CAS 113694-64-7|Fura 2 pentapotassium salt

Introduction:Basic information about CAS 113694-64-7|Fura 2 pentapotassium salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameFura 2 pentapotassium salt
CAS Number113694-64-7Molecular Weight831.98800
Density/Boiling Point983.5ºC at 760 mmHg
Molecular FormulaC29H22K5N3O14Melting Point/
MSDSChineseUSAFlash Point548.6ºC

Names

NameFura 2 pentapotassium salt
SynonymMore Synonyms

Fura 2 pentapotassium salt BiologicalActivity

DescriptionFura-2 pentapotassium is a scaled fluorescent dye that can be used for intracellular calcium imaging with the Kd value of 140 nM. Fura-2 pentapotassium has an emission wavelength of 510 nm and excitation wavelengths of 340 nm or 380 nm and the ratio of 340/380 fluorescence intensity is proportional to the intracellular Ca2+ level[1][2].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
In VitroFura-2 pentapotassium (10 μM, 2 min) can be used to detect changes in the concentration of calcium ions in neutrophils of heparinized peripheral blood[1]. Fura-2 pentapotassium (10 μM, 5 min) can be used as a calcium probe to assess the distribution of calcium ions within heart mitochondria without affecting the activity of it in rat[2].
References

[1]. Omar Rafael Alemán, et al. The Antibody Receptor Fc Gamma Receptor IIIb Induces Calcium Entry via Transient Receptor Potential Melastatin 2 in Human Neutrophils. Front Immunol. 2021 May 13;12:657393. doi: 10.3389/fimmu.2021.657393.

[2]. James G. McCormack, et al. Studies on mitochondrial Ca2+-transport and matrix Ca2+ using fura-2-loaded rat heart mitochondria. Biochim Biophys Acta. 1989 Mar 23;973(3):420-7.

Chemical & Physical Properties

Boiling Point983.5ºC at 760 mmHg
Molecular FormulaC29H22K5N3O14
Molecular Weight831.98800
Flash Point548.6ºC
Exact Mass830.92900
PSA264.76000
Vapour Pressure0mmHg at 25°C
InChIKeyDMJNHSMTLKZJJX-UHFFFAOYSA-N
SMILESCc1ccc(N(CC(=O)O)CC(=O)O)c(OCCOc2cc3cc(-c4ncc(C(=O)O)o4)oc3cc2N(CC(=O)O)CC(=O)O)c1.[K]

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADRNONH for all modes of transport

Synonyms

FURA 2 PENTAPOTASSIUM SALT
Fura-2,pentapotassium salt
MFCD00083328
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