CAS 80-06-8|1,1-Bis(p-chlorophenyl)methyl-carbinol

dehydrochlorinase[1]

[1]. Maestre-Serrano R, et al. Susceptibility to insecticides and resistance mechanisms in Aedes aegypti from the Colombian Caribbean Region. Pestic Biochem Physiol. 2014 Nov;116:63-73.  

[2]. W. R. Halliday, et al. Inheritance of Resistance to Permethrin and DDT in the Southern House Mosquito (Diptera: Culicidae), Journal of Economic Entomology, Volume 78, Issue 4, 1 August 1985, Pages 762–767,

CHEMICAL IDENTIFICATION

RTECS NUMBER :

DC7875000

CHEMICAL NAME :

Benzhydrol, 4,4'-dichloro-alpha-methyl-

CAS REGISTRY NUMBER :

80-06-8

BEILSTEIN REFERENCE NO. :

2505345

LAST UPDATED :

199612

DATA ITEMS CITED :

4

MOLECULAR FORMULA :

C14-H12-Cl2-O

MOLECULAR WEIGHT :

267.16

WISWESSER LINE NOTATION :

GR DXQ1&R DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

500 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

ARSIM* Agricultural Research Service, USDA Information Memorandum. (Beltsville, MD 20705) Volume(issue)/page/year: 20,8,1966

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

10 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

SPEADM Special Publication of the Entomological Society of America. (4603 Calvert Rd., College Park, MD 20740) Volume(issue)/page/year: 78-1,15,1978

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

725 mg/kg

TOXIC EFFECTS :

Behavioral - tremor Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :

OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,148,1968

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

750 mg/kg

TOXIC EFFECTS :

Behavioral - changes in motor activity (specific assay)

REFERENCE :

PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 72,304,1949

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