Introduction:Basic information about CAS 541-05-9|hexamethylcyclotrisiloxane, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently.
Toxicol. Appl. Pharmacol. 284(1) , 54-64, (2015)
Many persistent organic pollutants (POPs) accumulate readily in polar bears because of their position as apex predators in Arctic food webs. The pregnane X receptor (PXR, formally NR1I2, here proposed...
Effect of silicone on the collagen fibrillogenesis and stability.
J. Pharm. Sci. 104(4) , 1275-81, (2015)
Collagen, the most abundant protein in mammals, is able to form fibrils, which have central role in tissue repair, fibrosis, and tumor invasion. As a component of skin, tendons, and cartilages, this p...