CAS 19063-57-1|7-aminocoumarin

Introduction:Basic information about CAS 19063-57-1|7-aminocoumarin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name7-aminocoumarin
CAS Number19063-57-1Molecular Weight161.157
Density1.4±0.1 g/cm3Boiling Point381.4±37.0 °C at 760 mmHg
Molecular FormulaC9H7NO2Melting Point207-210°C (lit.)
MSDS/Flash Point219.3±24.0 °C

Names

Name7-aminochromen-2-one
SynonymMore Synonyms

7-aminocoumarin BiologicalActivity

Description7-Aminocoumarin is a pH-insensitive blue fluorophore. 7-Aminocoumarin is widely used as laser dyes in the blue-green region. 7-Aminocoumarin can be used to tag recombinant proteins on the cell surface and inside living cells through PRIME (probe incorporation mediated by enzymes). 7-Aminocoumarin can be visualized in acidic organelles such as endosomes[1][2].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. Jin X, et al. Synthesis of 7-aminocoumarin by Buchwald-Hartwig cross coupling for specific protein labeling in living cells. Chembiochem. 2011 Jan 3;12(1):65-70.

[2]. Pedone A. Role of Solvent on Charge Transfer in 7-Aminocoumarin Dyes: New Hints from TD-CAM-B3LYP and State Specific PCM Calculations. J Chem Theory Comput. 2013 Sep 10;9(9):4087-96.

Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point381.4±37.0 °C at 760 mmHg
Melting Point207-210°C (lit.)
Molecular FormulaC9H7NO2
Molecular Weight161.157
Flash Point219.3±24.0 °C
Exact Mass161.047684
PSA56.23000
LogP0.09
Vapour Pressure0.0±0.9 mmHg at 25°C
Index of Refraction1.659
InChIKeyRRHXPUCIXLAHIY-UHFFFAOYSA-N
SMILESNc1ccc2ccc(=O)oc2c1
Storage condition-20°C

Safety Information

Hazard CodesXi
HS Code2932209090

Customs

HS Code2932209090
Summary2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

7-Amino-2H-chromen-2-one
2H-1-Benzopyran-2-one, 7-amino-
7-Amino-2H-1-benzopyran-2-one
7-aminocoumarin
2H-1-Benzopyran-2-one,7-amino
7-amino coumarin
7-amino-chromen-2-one
7-Amino-cumarin
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