Introduction：Basic information about CAS 21852-80-2|Falcarinol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Falcarinol |
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| CAS Number | 21852-80-2 | Molecular Weight | 244.372 |
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| Density | 0.9±0.1 g/cm3 | Boiling Point | 370.6±42.0 °C at 760 mmHg |
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| Molecular Formula | C17H24O | Melting Point | / |
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| MSDS | / | Flash Point | 163.4±20.9 °C |
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Names
| Name | 1,9-Heptadecadiene-4,6-diyn-3-ol |
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| Synonym | More Synonyms |
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Falcarinol BiologicalActivity
| Description | Falcarinol (Panaxynol) is a natural, orally active Hsp90 inhibitor targeting both the N-terminal and C-terminal of Hsp90 with limited toxicities. Falcarinol (Panaxynol) induces apoptosis[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Metabolic Enzyme/Protease >>HSPSignaling Pathways >>Cell Cycle/DNA Damage >>HSP |
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| In Vitro | Panaxynol inhibits the sphere-forming ability of NSCLC CSCs by inducing apoptosis. Panaxynol suppresses the viability of NSCLC cells with no effects on normal cells[1]. |
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| References | [1]. Le HT, et al. Panaxynol, a natural Hsp90 inhibitor, effectively targets both lung cancer stem and non-stem cells. Cancer Lett. 2018 Jan 1;412:297-307. |
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Chemical & Physical Properties
| Density | 0.9±0.1 g/cm3 |
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| Boiling Point | 370.6±42.0 °C at 760 mmHg |
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| Molecular Formula | C17H24O |
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| Molecular Weight | 244.372 |
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| Flash Point | 163.4±20.9 °C |
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| Exact Mass | 244.182709 |
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| PSA | 20.23000 |
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| LogP | 6.96 |
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| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
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| Index of Refraction | 1.507 |
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| InChIKey | UGJAEDFOKNAMQD-QXPKXGMISA-N |
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| SMILES | C=CC(O)C#CC#CCC=CCCCCCCC |
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Safety Information
Customs
| HS Code | 2905290000 |
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| Summary | 2905290000 unsaturated monohydric alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
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Synonyms
| Carotatoxin |
| (-)-Falcarinol |
| (-)-Carotatoxin |
| 1,9-Heptadecadiene-4,6-diyn-3-ol, (3R,9Z)- |
| (-)-Panaxynol |
| (−)-(3R)-falcarinol |
| (3R,9Z)-1,9-Heptadecadiene-4,6-diyn-3-ol |
| Falcarinol |
| Panaxynol |
| (3R,9Z)-Heptadeca-1,9-diene-4,6-diyn-3-ol |
| Falcarinol |
