CAS 120595-72-4|2-AMINO-6-CHLORO-9-(BETA-D-2-DEOXYRIBOFURANOSYL)PURINE

Introduction：Basic information about CAS 120595-72-4|2-AMINO-6-CHLORO-9-(BETA-D-2-DEOXYRIBOFURANOSYL)PURINE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	2-AMINO-6-CHLORO-9-(BETA-D-2-DEOXYRIBOFURANOSYL)PURINE
CAS Number	120595-72-4	Molecular Weight	285.69
Density	/	Boiling Point	/
Molecular Formula	C₁₀H₁₂ClN₅O₃	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	(2R,3S,5S)-5-(2-amino-6-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
Synonym	More Synonyms

BiologicalActivity

Description	2-Amino-6-chloropurine-9-beta-D-(2’-deoxy)riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

Molecular Formula	C₁₀H₁₂ClN₅O₃
Molecular Weight	285.69
Exact Mass	285.06300
PSA	119.31000
LogP	0.28380
InChIKey	LEDIVMUMDVEFRG-KVQBGUIXSA-N
SMILES	Nc1nc(Cl)c2ncn(C3CC(O)C(CO)O3)c2n1

Synonyms

2-AMINO-6-CHLOROPURINE-2`-DEOXYRIBOSIDE

2-amino-6-chloro-2'-deoxyguanosine

carbocyclic 2-amino-6-chloro-2'-deoxyadenosine

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