CAS 4372-67-2|8-azidoadenosine

Introduction:Basic information about CAS 4372-67-2|8-azidoadenosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name8-azidoadenosine
CAS Number4372-67-2Molecular Weight308.25
Density/Boiling Point/
Molecular FormulaC10H12N8O4Melting Point>200ºC (dec.)
MSDS/Flash Point/

Names

Name8-Azido Adenosine
SynonymMore Synonyms

8-azidoadenosine BiologicalActivity

Description8-Azidoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog
References

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

Chemical & Physical Properties

Melting Point>200ºC (dec.)
Molecular FormulaC10H12N8O4
Molecular Weight308.25
Exact Mass308.09800
PSA189.29000
InChIKeyKYJLJOJCMUFWDY-UUOKFMHZSA-N
SMILES[N-]=[N+]=Nc1nc2c(N)ncnc2n1C1OC(CO)C(O)C1O
Storage conditionAmber Vial, Refrigerator, Under Inert Atmosphere

Synonyms

8-azidoadenosine
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