Introduction：Basic information about CAS 1131-18-6|3-Methyl-1-phenyl-1H-pyrazol-5-amine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 3-Methyl-1-phenyl-1H-pyrazol-5-amine |
|---|
| CAS Number | 1131-18-6 | Molecular Weight | 173.214 |
|---|
| Density | 1.2±0.1 g/cm3 | Boiling Point | 333.0±22.0 °C at 760 mmHg |
|---|
| Molecular Formula | C10H11N3 | Melting Point | 114-117 °C(lit.) |
|---|
| MSDS | ChineseUSA | Flash Point | 155.2±22.3 °C |
|---|
| Symbol |
GHS07 | Signal Word | Warning |
|---|
Names
| Name | 5-Amino-3-methyl-1-phenylpyrazole |
|---|
| Synonym | More Synonyms |
|---|
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|
| Boiling Point | 333.0±22.0 °C at 760 mmHg |
|---|
| Melting Point | 114-117 °C(lit.) |
|---|
| Molecular Formula | C10H11N3 |
|---|
| Molecular Weight | 173.214 |
|---|
| Flash Point | 155.2±22.3 °C |
|---|
| Exact Mass | 173.095291 |
|---|
| PSA | 43.84000 |
|---|
| LogP | 1.96 |
|---|
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
|---|
| Index of Refraction | 1.625 |
|---|
| InChIKey | FMKMKBLHMONXJM-UHFFFAOYSA-N |
|---|
| SMILES | Cc1cc(N)n(-c2ccccc2)n1 |
|---|
Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- UQ4990000
- CHEMICAL NAME :
- 1H-Pyrazole-5-amine, 3-methyl-1-phenyl-
- CAS REGISTRY NUMBER :
- 1131-18-6
- BEILSTEIN REFERENCE NO. :
- 0140666
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C10-H11-N3
- MOLECULAR WEIGHT :
- 173.24
- WISWESSER LINE NOTATION :
- T5NNJ AR& C1 EZ
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2500 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- LONZA# Personal Communication from LONZA Ltd., CH-4002, Basel, Switzerland Volume(issue)/page/year: 03FEB1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1300 mg/kg
- TOXIC EFFECTS :
- Behavioral - hallucinations, distorted perceptions Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- LONZA# Personal Communication from LONZA Ltd., CH-4002, Basel, Switzerland Volume(issue)/page/year: 03FEB1981
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 27,295,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity
- REFERENCE :
- LONZA# Personal Communication from LONZA Ltd., CH-4002, Basel, Switzerland Volume(issue)/page/year: 03FEB1981
|
Safety Information
| Symbol |
GHS07 |
|---|
| Signal Word | Warning |
|---|
| Hazard Statements | H315-H319-H335 |
|---|
| Precautionary Statements | P261-P305 + P351 + P338 |
|---|
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
|---|
| Hazard Codes | Xi: Irritant; |
|---|
| Risk Phrases | R36/37/38 |
|---|
| Safety Phrases | S26-S36 |
|---|
| RIDADR | NONH for all modes of transport |
|---|
| WGK Germany | 3 |
|---|
| RTECS | UQ4990000 |
|---|
| HS Code | 2933199090 |
|---|
Customs
| HS Code | 2933199090 |
|---|
| Summary | 2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
|---|
Articles4
More Articles
| Synthesis of Newly Substituted Pyrazoles and Substituted Pyrazolo [3, 4-b] Pyridines Based on 5-Amino-3-Methyl-1-Phenylpyrazole. El-Emary TI. J. Chin. Chem. Soc. 54(2) , 507-518, (2007)
| |
| An unexpected chemical behavior of 5-N-(benzotriazol-1-ylmethyl) amino-3-tert-butyl-1-phenylpyrazole. Abonia R, et al. Tetrahedron Lett. 43(22) , 5617-5620, (2002)
| |
| The synthesis of fused and pendant pyrazole heterocyclic compounds from 5-amino-3-methyl-1-phenylpyrazole and their evaluation as fluorescent brightening agents. Tagdiwala PV and Rangnekar DW. J. Chem. Technol. Biotechnol. 38(2) , 77-84, (1987)
| |
Synonyms
| 5-methyl-2-phenylpyrazol-3-amine |
| 1H-Pyrazol-5-amine, 3-methyl-1-phenyl- |
| 5-AMINO-3-METHYL-1-PHENYLPYRAZOLE |
| MFCD00020727 |
| T5NNJ AR& C1 EZ |
| 3-Methyl-1-phenyl-1H-pyrazol-5-amine |
| EINECS 214-463-3 |
