Introduction：Basic information about CAS 118-23-0|bromazine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | bromazine |
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| CAS Number | 118-23-0 | Molecular Weight | 334.25100 |
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| Density | 1.259g/cm3 | Boiling Point | 397.3ºC at 760mmHg |
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| Molecular Formula | C17H20BrNO | Melting Point | / |
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| MSDS | / | Flash Point | 194.1ºC |
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Names
| Name | bromazine |
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| Synonym | More Synonyms |
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bromazine BiologicalActivity
| Description | Bromodiphenhydramine (Ambodryl) is a potent antihistamine with antimicrobial property. Bromodiphenhydramine inhibits a large number of Gram negative and Gram positive bacteria. Bromodiphenhydramine can be used for cutaneous allergies research[1][2][3]. |
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| Related Catalog | Signaling Pathways >>Immunology/Inflammation >>Histamine ReceptorResearch Areas >>InfectionResearch Areas >>Inflammation/ImmunologySignaling Pathways >>GPCR/G Protein >>Histamine ReceptorSignaling Pathways >>Anti-infection >>Bacterial |
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| In Vivo | Bromodiphenhydramine (1.5 and 3 μg/g, single) protects mice against a challenge with a virulent strain of Salmonella typhimurium, and also significantly reduces the multiplication of this organism in the liver, spleen and blood of the protected animals in comparison with the unprotected controls[2]. |
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| References | [1]. MOLINA EB. [A new antihistaminic, bromodiphenhydramine hydrochloride, in the control of cutaneous allergies]. Sem Med. 1960 Jul 11;117:151-2. Spanish. [2]. Dastidar SG, et al. Antibacterial activity of ambodryl and benadryl. J Appl Bacteriol. 1976 Oct;41(2):209-14. [3]. Ray S, et al. Studies on synergism between penicillins and ambodryl (bromodiphenhydramine HCl), an antihistamine with antimicrobial property. Indian J Exp Biol. 1990 Mar;28(3):253-8. |
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Chemical & Physical Properties
| Density | 1.259g/cm3 |
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| Boiling Point | 397.3ºC at 760mmHg |
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| Molecular Formula | C17H20BrNO |
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| Molecular Weight | 334.25100 |
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| Flash Point | 194.1ºC |
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| Exact Mass | 333.07300 |
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| PSA | 12.47000 |
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| LogP | 4.11670 |
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| InChIKey | NUNIWXHYABYXKF-UHFFFAOYSA-N |
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| SMILES | CN(C)CCOC(c1ccccc1)c1ccc(Br)cc1 |
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Safety Information
Customs
| HS Code | 2922199090 |
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| Summary | 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| Histabromamine |
| N-2-(4-bromobenzhydryloxy)ethyldimethylamine |
| EINECS 204-238-8 |
| bromodiphenhydramine |
| Bromanautine |
| Bromo-Benadryl |
| Ethanamine,2-(4-bromophenyl)phenylmethoxy-N,N-dimethyl |
