Introduction：Basic information about CAS 952-23-8|Proflavine hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Proflavine hydrochloride |
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| CAS Number | 952-23-8 | Molecular Weight | 245.708 |
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| Density | 1.346g/cm3 | Boiling Point | 506.9ºC at 760mmHg |
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| Molecular Formula | C13H12ClN3 | Melting Point | 270 °C |
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| MSDS | / | Flash Point | 292.9ºC |
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Names
| Name | 3,6-diaminoacridine monohydrochloride |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.346g/cm3 |
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| Boiling Point | 506.9ºC at 760mmHg |
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| Melting Point | 270 °C |
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| Molecular Formula | C13H12ClN3 |
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| Molecular Weight | 245.708 |
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| Flash Point | 292.9ºC |
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| Exact Mass | 245.071976 |
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| PSA | 64.93000 |
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| LogP | 4.51680 |
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| InChIKey | PBBGTVBGXBUVLT-UHFFFAOYSA-N |
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| SMILES | Cl.Nc1ccc2cc3ccc(N)cc3nc2c1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- AR9064000
- CHEMICAL NAME :
- Acridine, 3,6-diamino-, monohydrochloride
- CAS REGISTRY NUMBER :
- 952-23-8
- LAST UPDATED :
- 199603
- DATA ITEMS CITED :
- 14
- MOLECULAR FORMULA :
- C13-H11-N3.Cl-H
- MOLECULAR WEIGHT :
- 245.73
- WISWESSER LINE NOTATION :
- T C666 BNJ EZ MZ &GH
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 190 mg/kg
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - hematuria
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5040 mg/kg/6W-C
- TOXIC EFFECTS :
- Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 27 gm/kg/109W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 35 gm/kg/104W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
MUTATION DATA - TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - mouse Lymphocyte
- DOSE/DURATION :
- 500 ug/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 204,323,1988 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 24,195,1980 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 24,195,1980 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987
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Safety Information
| Risk Phrases | R40 |
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| RTECS | AR9064000 |
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| HS Code | 2933990090 |
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Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| chlorhydrate de diamino-3,6 acridine |
| 3,6-Acridinediamine hydrochloride |
| N,N,N',N'-de-tetramethyl-acridine orange |
| acridine-3,6-diamine hydrochloride |
| 3,6-diaminoacridine monohydrochloride |
| PROFLAVINHYDROCHLORIDE |
| 3,6-Acridinediamine, hydrochloride (1:1) |
| Proflavine hydrochloride |
| 3,6-Acridinediamine, hydrochloride (8CI) |
| 3,6-diaminoacridine-hydrochloride |
| EUFLAVIN |
| PROFLAVIN MONOHYDROCHLORIDE |
| 3,6-Acridinediamine hydrochloride (1:1) |
| PROFLAVINESALTS |
| 3,6-DiaminoacridineHCl |
| Proflavine monohydrochloride |
| EINECS 213-459-9 |
| 3,6-Diaminoacridine Hydrochloride |
| MFCD00066867 |
