CAS 59865-15-5|Dihydro Cyclosporin A
Introduction：Basic information about CAS 59865-15-5|Dihydro Cyclosporin A, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Dihydro Cyclosporin A | ||
|---|---|---|---|
| CAS Number | 59865-15-5 | Molecular Weight | 1204.627 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 1285.3±65.0 °C at 760 mmHg |
| Molecular Formula | C62H113N11O12 | Melting Point | 120-125ºC |
| MSDS | / | Flash Point | 731.1±34.3 °C |
Names
| Name | Dihydro Cyclosporin A |
|---|---|
| Synonym | More Synonyms |
Dihydro Cyclosporin A BiologicalActivity
| Description | Dihydrocyclosporin A is a derivative of Cyclosporine A (HY-B0579). Dihydrocyclosporin A significantly inhibites promastigotes and intracellular amastigotes. Dihydrocyclosporin A is highly cytotoxic[1]. |
|---|---|
| Related Catalog | Research Areas >>Infection |
| References | [1]. Zheng ZW, et al. Evaluation of in vitro antileishmanial efficacy of cyclosporin A and its non-immunosuppressive derivative, dihydrocyclosporin A. Parasit Vectors. 2020 Feb 21;13(1):94. |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 1285.3±65.0 °C at 760 mmHg |
| Melting Point | 120-125ºC |
| Molecular Formula | C62H113N11O12 |
| Molecular Weight | 1204.627 |
| Flash Point | 731.1±34.3 °C |
| Exact Mass | 1203.857056 |
| PSA | 278.80000 |
| LogP | 3.67 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.465 |
| InChIKey | TYFOVYYNQGNDKH-CJOIJTDBSA-N |
| SMILES | CCCCC(C)C(O)C1C(=O)NC(CC)C(=O)N(C)CC(=O)N(C)C(CC(C)C)C(=O)NC(C(C)C)C(=O)N(C)C(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)N(C)C(CC(C)C)C(=O)N(C)C(CC(C)C)C(=O)N(C)C(C(C)C)C(=O)N1C |
| Storage condition | -20°C |
Synonyms
| 6-[(2S,3R,4R)-3-Hydroxy-4-Methyl-2-(MethylaMino)octanoic acid]cyclosporin A |
| <DH-MeBmt>cyclosporin |
| dihydro-CSA |
| DIHYDROCYCLOSPORIN A |
| Dihydrocyclosporin |
| (3S,6S,9S,12R,15S,18S,21S,24S,30S)-30-Ethyl-33-[(1R,2R)-1-hydroxy-2-methylhexyl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone |
| (3R,4R)-3-Hydroxy-N-methyl-5-propylcyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-) |
| (3R,4R)-3-Hydroxy-4,N-dimethyl-5-propylcyclo[L-Nva-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-] |
| 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone, 30-ethyl-33-[(1R,2R)-1-hydroxy-2-methylhexyl]-1,4,7,10,12,15,19,25,28-nonamethyl-3,21-bis(1-methylethyl)-6,9,18,24-tetrakis(2-methylpropyl)-, (3S,6S,9S,12R,15S,18S,21S,24S,30S)- |
| Cyclosporin Impurity 10 |
