Introduction：Basic information about CAS 95789-30-3|Cefotiam, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Cefotiam |
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| CAS Number | 95789-30-3 | Molecular Weight | 525.628 |
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| Density | 1.8±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C27H39Cl2N9O7S3 | Melting Point | 120-130°C |
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| MSDS | / | Flash Point | / |
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Names
| Name | cefotiam hexetil dihydrochloride |
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| Synonym | More Synonyms |
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Cefotiam BiologicalActivity
| Description | Cefotiam hexetil hydrochloride (CTM-HE) is an oral third-generation cephalosporin, which is a prodrug of cefotiam, but has no anti-bacterial property. Cefotiam is an antibiotic[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| References | [1]. Querol-Ferrer V, et al. The blood binding of cefotiam and cyclohexanol, metabolites of the prodrug cefotiam hexetil, in-vitro. J Pharm Pharmacol. 1991 Dec;43(12):863-6. |
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Chemical & Physical Properties
| Density | 1.8±0.1 g/cm3 |
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| Melting Point | 120-130°C |
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| Molecular Formula | C27H39Cl2N9O7S3 |
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| Molecular Weight | 525.628 |
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| Exact Mass | 525.103516 |
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| PSA | 275.83000 |
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| LogP | 0.24 |
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| Index of Refraction | 1.855 |
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| InChIKey | FFSANQNELHESQJ-LWBICVDYSA-N |
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| SMILES | CC(OC(=O)OC1CCCCC1)OC(=O)C1=C(CSc2nnnn2CCN(C)C)CSC2C(NC(=O)Cc3csc(N)n3)C(=O)N12.Cl.Cl |
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| Storage condition | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
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Safety Information
Synonyms
| (6R,7R)-7-{[(2-amino-1,3-thiazol-4-yl)acetyl]amino}-3-[({1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl}thio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| Cefotiam Hexetil Hydrochloride |
| Cefotiam |
| (6R,7R)-7-{[(2-Amino-1,3-thiazol-4-yl)acetyl]amino}-3-[({1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl}sulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| cefotiamum [INN_la] |
| 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-, (6R,7R)- |
| 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[2-(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-, (6R,7R)- |
| 7b-[2-(Aminothiazol-4-yl)acetamido]-3-[[[1-(2-dimethylaminoethyl)-1H-tetrazol-5-yl]thio]methyl]ceph-3-em-4-carboxylic Acid |
