Introduction：Basic information about CAS 35665-38-4|Fmoc-Gly-Gly-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fmoc-Gly-Gly-OH |
|---|
| CAS Number | 35665-38-4 | Molecular Weight | 354.357 |
|---|
| Density | 1.3±0.1 g/cm3 | Boiling Point | 684.1±45.0 °C at 760 mmHg |
|---|
| Molecular Formula | C19H18N2O5 | Melting Point | 182 °C |
|---|
| MSDS | / | Flash Point | 367.5±28.7 °C |
|---|
Names
| Name | 2-[[2-(9H-fluoren-9-ylmethoxycarbonylamino)acetyl]amino]acetic acid |
|---|
| Synonym | More Synonyms |
|---|
Fmoc-Gly-Gly-OH BiologicalActivity
| Description | Fmoc-Gly-Gly-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker |
|---|
| Target | Cleavable |
|---|
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. |
|---|
| References | [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. |
|---|
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|
| Boiling Point | 684.1±45.0 °C at 760 mmHg |
|---|
| Melting Point | 182 °C |
|---|
| Molecular Formula | C19H18N2O5 |
|---|
| Molecular Weight | 354.357 |
|---|
| Flash Point | 367.5±28.7 °C |
|---|
| Exact Mass | 354.121582 |
|---|
| PSA | 104.73000 |
|---|
| LogP | 2.37 |
|---|
| Appearance of Characters | Powder | White |
|---|
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
|---|
| Index of Refraction | 1.613 |
|---|
| InChIKey | FBKUOPULLUJMOC-UHFFFAOYSA-N |
|---|
| SMILES | O=C(O)CNC(=O)CNC(=O)OCC1c2ccccc2-c2ccccc21 |
|---|
| Storage condition | -15°C |
|---|
Safety Information
Customs
| HS Code | 2924299090 |
|---|
| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
|---|
Synonyms
| N-9-fluorenylmethoxycarbonyl-glycyl-glycine |
| Fmoc-Gly-Gly |
| 2-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)acetamido)acetic acid |
| Fmoc-Gly-Gly-OH |
| Glycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycyl- |
| N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycylglycine |
| FMOC-GLYCYL-GLYCINE |
