Introduction：Basic information about CAS 304-28-9|2,7-diacetylaminofluorene, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2,7-diacetylaminofluorene |
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| CAS Number | 304-28-9 | Molecular Weight | 280.321 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 614.6±48.0 °C at 760 mmHg |
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| Molecular Formula | C17H16N2O2 | Melting Point | / |
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| MSDS | / | Flash Point | 246.9±29.7 °C |
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Names
| Name | N-(7-acetamido-9H-fluoren-2-yl)acetamide |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 614.6±48.0 °C at 760 mmHg |
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| Molecular Formula | C17H16N2O2 |
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| Molecular Weight | 280.321 |
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| Flash Point | 246.9±29.7 °C |
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| Exact Mass | 280.121185 |
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| PSA | 58.20000 |
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| LogP | 1.89 |
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| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
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| Index of Refraction | 1.694 |
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| InChIKey | XBZBRCVCSVLJJZ-UHFFFAOYSA-N |
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| SMILES | CC(=O)Nc1ccc2c(c1)Cc1cc(NC(C)=O)ccc1-2 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- AC0700000
- CHEMICAL NAME :
- Acetamide, N,N'-fluoren-2,7-ylenebis-
- CAS REGISTRY NUMBER :
- 304-28-9
- BEILSTEIN REFERENCE NO. :
- 2815543
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 18
- MOLECULAR FORMULA :
- C17-H16-N2-O2
- MOLECULAR WEIGHT :
- 280.35
- WISWESSER LINE NOTATION :
- L B656 HHJ EMV1 KMV1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4830 mg/kg/46W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2044 mg/kg/29W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - bronchiogenic carcinoma Blood - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2100 mg/kg/13W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Blood - leukemia
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 1200 mg/kg/34W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Vascular - tumors Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1830 mg/kg/32W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Brain and Coverings - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2060 mg/kg/34W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - bronchiogenic carcinoma Blood - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2250 mg/kg/21W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Skin and Appendages - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6480 mg/kg/26W-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Cardiac - tumors Lungs, Thorax, or Respiration - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 7668 mg/kg/30W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2800 mg/kg/32W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 228 gm/kg/26W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - leukemia
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2035 mg/kg/34W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors
MUTATION DATA - TEST SYSTEM :
- Rodent - rat
- DOSE/DURATION :
- 315 mg/kg/3W
- REFERENCE :
- JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 54,1245,1975
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Synonyms
| 2,7-Diacetamidofluorene |
| 2,7-diacetylamidofluorene |
| N,N'-9H-fluorene-2,7-diylbisacetamide |
| N,N'-fluorene-2,7-diyl-bis-acetamide |
| 2.7-Bis-acetamino-fluoren |
| 2,7-diacetylaminofluorene |
| Acetamide, N,N'-9H-fluorene-2,7-diylbis- |
| N,N'-9H-Fluorene-2,7-diyldiacetamide |
| 2,7-Fluorenylbisacetamide |
| 2,5-DIMETHYL-4'-PIPERIDINOMETHYL BENZOPHENONE |
| 2,7-Acetylaminofluorene |
| 2,7-Di(acetamido)fluorene |
| N,N'-Fluoren-2,7-diyl-bis-acetamid |
| EINECS 206-153-1 |
| 2,7-Faa |
