Introduction：Basic information about CAS 118-08-1|Hydrastine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Hydrastine |
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| CAS Number | 118-08-1 | Molecular Weight | 383.39500 |
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| Density | 1.339g/cm3 | Boiling Point | 548.8ºC at 760mmHg |
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| Molecular Formula | C21H21NO6 | Melting Point | 132ºC |
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| MSDS | / | Flash Point | 285.7ºC |
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| Symbol |
GHS07 | Signal Word | Warning |
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Names
| Name | (-)-β-HYDRASTINE |
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| Synonym | More Synonyms |
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Hydrastine BiologicalActivity
| Description | Hydrastine is a natural alkaloid which is present in Hydrastis canadensis and other plants of the ranunculaceae family. |
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| Related Catalog | Signaling Pathways >>Others >>OthersNatural Products >>AlkaloidResearch Areas >>Others |
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Chemical & Physical Properties
| Density | 1.339g/cm3 |
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| Boiling Point | 548.8ºC at 760mmHg |
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| Melting Point | 132ºC |
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| Molecular Formula | C21H21NO6 |
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| Molecular Weight | 383.39500 |
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| Flash Point | 285.7ºC |
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| Exact Mass | 383.13700 |
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| PSA | 66.46000 |
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| LogP | 2.81110 |
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| Vapour Pressure | 4.28E-12mmHg at 25°C |
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| Index of Refraction | 1.614 |
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| InChIKey | JZUTXVTYJDCMDU-MOPGFXCFSA-N |
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| SMILES | COc1ccc2c(c1OC)C(=O)OC2C1c2cc3c(cc2CCN1C)OCO3 |
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| Storage condition | −20°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- MU6030000
- CHEMICAL NAME :
- Hydrastine
- CAS REGISTRY NUMBER :
- 118-08-1
- BEILSTEIN REFERENCE NO. :
- 0098575
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C21-H21-N-O6
- MOLECULAR WEIGHT :
- 383.43
- WISWESSER LINE NOTATION :
- T C566 DO FO LN EH&&TJ L M- DT56 BVO DHJ HO1 IO1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 104 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada)
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Safety Information
| Symbol |
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H302 + H312 + H332 |
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| Precautionary Statements | P261-P280-P301 + P312 + P330 |
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| Hazard Codes | Xn: Harmful; |
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| Risk Phrases | 20/21/22 |
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| Safety Phrases | S36 |
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| RIDADR | 1544 |
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| WGK Germany | 3 |
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| RTECS | MU6030000 |
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| Packaging Group | III |
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| Hazard Class | 6.1(b) |
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Synonyms
| Hydrastine (10 mg) |
| quinolin-5-yl) |
| HYDRASTINE |
| Hydrastinebase |
| (-)-Beta-Hydrastine |
| EINECS 204-233-0 |
| MFCD00152561 |
| (-)-B-HYDIASTINE |
| l-hydrastine |
| HYDRASTINE,(-)-B |
