Introduction：Basic information about CAS 38873-55-1|Furobufen, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Furobufen |
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| CAS Number | 38873-55-1 | Molecular Weight | 268.26400 |
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| Density | 1.343g/cm3 | Boiling Point | 509.8ºC at 760 mmHg |
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| Molecular Formula | C16H12O4 | Melting Point | / |
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| MSDS | / | Flash Point | 262.1ºC |
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Names
| Name | 4-dibenzofuran-2-yl-4-oxobutanoic acid |
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| Synonym | More Synonyms |
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Furobufen BiologicalActivity
| Description | Furobufen, an anti-inflammatory agent, produces antiarthritic, antipyretic effects. Furobufen has an analgesic effect in inflamed tissue[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/ImmunologyResearch Areas >>Neurological Disease |
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| In Vivo | Furobufen (po; 10, 30, 90 mg/kg; once daily; 7 days) produces a dose-related inhibition of the paw edema produced by carrageenan in male rats weighing 180-200 g[1]. |
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| References | [1]. Martel RR, et al. Anti-inflammatory properties of furobufen. Can J Physiol Pharmacol. 1974 Jun;52(3):669-73. |
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Chemical & Physical Properties
| Density | 1.343g/cm3 |
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| Boiling Point | 509.8ºC at 760 mmHg |
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| Molecular Formula | C16H12O4 |
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| Molecular Weight | 268.26400 |
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| Flash Point | 262.1ºC |
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| Exact Mass | 268.07400 |
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| PSA | 67.51000 |
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| LogP | 3.63350 |
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| Index of Refraction | 1.676 |
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| InChIKey | LQVMQEYROPXMQH-UHFFFAOYSA-N |
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| SMILES | O=C(O)CCC(=O)c1ccc2oc3ccccc3c2c1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- HP4930000
- CHEMICAL NAME :
- 2-Dibenzofuranbutanoic acid, gamma-oxo-
- CAS REGISTRY NUMBER :
- 38873-55-1
- BEILSTEIN REFERENCE NO. :
- 0250326
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C16-H12-O4
- MOLECULAR WEIGHT :
- 268.28
- WISWESSER LINE NOTATION :
- T B656 HOJ DV2VQ
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1283 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CJPPA3 Canadian Journal of Physiology and Pharmacology. (National Research Council of Canada, Publication Sales and Distribution, Ottawa ON K1A OR6, Canada) V.42- 1964- Volume(issue)/page/year: 52,669,1974
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Safety Information
Customs
| HS Code | 2932999099 |
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| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 4-dibenzofuran-2-yl-4-oxo-butyric acid |
| Furobufenum [INN-Latin] |
| Furobufene [French] |
| Furobufeno [INN-Spanish] |
| Furobufen |
| Furobufeno [Spanish] |
| 4-Dibenzofuran-2-yl-4-oxo-buttersaeure |
| Furobufene [INN-French] |
