CAS 110-57-6|trans-1,4-Dichlorobutene
Introduction：Basic information about CAS 110-57-6|trans-1,4-Dichlorobutene, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | trans-1,4-Dichlorobutene | ||
|---|---|---|---|
| CAS Number | 110-57-6 | Molecular Weight | 124.996 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 155.5±0.0 °C at 760 mmHg |
| Molecular Formula | C4H6Cl2 | Melting Point | 1-3ºC(lit.) |
| MSDS | ChineseUSA | Flash Point | 54.4±0.0 °C |
| Symbol | GHS02, GHS05, GHS06 | Signal Word | Danger |
Names
| Name | trans-1,4-Dichloro-2-butene |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 155.5±0.0 °C at 760 mmHg |
| Melting Point | 1-3ºC(lit.) |
| Molecular Formula | C4H6Cl2 |
| Molecular Weight | 124.996 |
| Flash Point | 54.4±0.0 °C |
| Exact Mass | 123.984657 |
| LogP | 1.97 |
| Vapour Pressure | 3.9±0.2 mmHg at 25°C |
| Index of Refraction | 1.459 |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 86 ppm/4H
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Lungs, Thorax, or Respiration - other changes Gastrointestinal - changes in structure or function of salivary glands
- REFERENCE :
- AIHAM* Annual Meeting of American Industrial Hygiene Association. (Akron, OH) For publisher information, see AIHAAP. Volume(issue)/page/year: -,-,1968 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 150 mg/kg/77W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 150 mg/kg/77W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,149,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,149,1977 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987
Safety Information
| Symbol | GHS02, GHS05, GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H226-H301-H312-H314-H330 |
| Precautionary Statements | P260-P280-P284-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | T+,T,F,N |
| Risk Phrases | R10 |
| Safety Phrases | 53-23-26-36/37/39-45-36/37-99-61-60 |
| RIDADR | UN 3390 6.1/PG 1 |
| WGK Germany | 3 |
| RTECS | EM4903000 |
| Packaging Group | II |
| Hazard Class | 6.1(a) |
| HS Code | 2903299090 |
Customs
| HS Code | 2903299090 |
|---|---|
| Summary | 2903299090 other unsaturated chlorinated derivatives of acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
Articles15
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| Synthesis and biological properties of 9-(trans-4-hydroxy-2-buten-1-yl)adenine and guanine: open-chain analogues of neplanocin A. J. Med. Chem. 30(2) , 437-40, (1987) Alkylation of adenine (5a) or 2-amino-6-chloropurine (5b) with excess trans-1,4-dichloro-2-butene (4), effected by K2CO3 in dimethyl sulfoxide or tetra-n-butylammonium fluoride in tetrahydrofuran, led... | |
| Effect of isomers of swainsonine on glycosidase activity and glycoprotein processing. Biochemistry 26(9) , 2502-10, (1987) The chemical synthesis of swainsonine [(1S,2R,8R,8 alpha R)-trihydroxyindolizidine] from trans-1,4-dichloro-2-butene was previously described [Adams, C. E., Walker, F. J., & Sharpless, K. B. (1985) J.... |
Synonyms
| 2-Butene, 1,4-dichloro-, (E)- |
| Toluene,2,5-dichloro |
| trans-1,4-Dichlorobutene |
| (2E)-1,4-Dichloro-2-butene |
| 1,4-Dichloro-2-butene |
| Benzene,1,4-dichloro-2-methyl |
| trans 1,4-Dichloro-2-butene |
| (E)-1,4-Dichloro-2-butene |
| EINECS 203-779-7 |
| TRANS-1,4-DICHLORO-2-BUTYLENE |
| 2,5-dichloro-toluene |
| 2,5-Dichlor-toluol |
| 1,4-dichloro-toluene |
| MFCD00000988 |
| TRANS-1,4-DICHLOROBUT-2-ENE |
| 4-01-00-00787 (Beilstein Handbook Reference) |
| 2-Butene, 1,4-dichloro-, (2E)- |
| (2E)-1,4-dichlorobut-2-ene |
| but-2-ene, trans-1,4-dichloro- |
| Toluene,5-dichloro |
| 1,4-dichloro-2-methyl-benzene |
| TRANS-1,4-DICHLOR-2-BUTENE |
| 1,4-Dichloro-trans-2-butene |
| 2-Butene, 1,4-dichloro-, trans- |
| trans-1,4-Dichloro-2-butene |
