CAS 352438-69-8|2,4-D-d5

Introduction:Basic information about CAS 352438-69-8|2,4-D-d5, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name2,4-D-d5
CAS Number352438-69-8Molecular Weight210.06900
Density/Boiling Point/
Molecular FormulaC8HCl2D5O2Melting Point/
MSDS/Flash Point/

Names

Name2,4-dichlorophenoxy-3,5,6-d3-acetic-d2 acid
SynonymMore Synonyms

2,4-D-d5 BiologicalActivity

Description2,4-D-d5 is the deuterium labeled 2,4-D[1]. 2,4-D (2,4-Dichlorophenoxyacetic acid) is a selective systemic herbicide for the control of broad-leaved weeds. 2,4-D acts as a plant hormone, causing uncontrolled growth in the meristematic tissues. 2,4-D inhibits DNA and protein synthesis and thereby prevents normal plant growth and development[2].
Related CatalogSignaling Pathways >>Cell Cycle/DNA Damage >>DNA/RNA SynthesisResearch Areas >>Others
In VitroStable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Germaine KJ, et al. Bacterial endophyte-enhanced phytoremediation of the organochlorine herbicide 2,4-dichlorophenoxyacetic acid. FEMS Microbiol Ecol. 2006 Aug;57(2):302-10.  

Chemical & Physical Properties

Molecular FormulaC8HCl2D5O2
Molecular Weight210.06900
Exact Mass209.00600
PSA37.30000
LogP2.62050

Synonyms

2,4,6-cycloheptatriene-1-carbonitrile
CAS 352431-55-1|1-Chloroadamantane
CAS 352438-71-2|1,1-Diethoxy(2H4)ethane
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