CAS 3554-93-6|O-glycosylation-IN-1
| Common Name | O-glycosylation-IN-1 | ||
|---|---|---|---|
| CAS Number | 3554-93-6 | Molecular Weight | 311.33000 |
| Density | 1.34g/cm3 | Boiling Point | 594.9ºC at 760mmHg |
| Molecular Formula | C15H21NO6 | Melting Point | 201-203°C |
| MSDS | USA | Flash Point | 313.6ºC |
Names
| Name | BENZYL-2-ACETAMIDO-2-DEOXY-α-D-GALACTOPYRANOSIDE |
|---|---|
| Synonym | More Synonyms |
O-glycosylation-IN-1 BiologicalActivity
| Description | O-glycosylation-IN-1 is a potent O-glycosylation inhibitor and is used to reduce mucin on cell surfaces. O-glycosylation-IN-1 inhibits the synthesis of mucin O-glycosylation of cellular models of human pancreatic cancer[1]. |
|---|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
| Target | O-glycosylation[1] |
| References | [1]. Kalra AV, et al. Mucin impedes cytotoxic effect of 5-FU against growth of human pancreatic cancer cells: overcoming cellular barriers for therapeutic gain. Br J Cancer. 2007 Oct 8;97(7):910-8. Epub 2007 Oct 2. |
Chemical & Physical Properties
| Density | 1.34g/cm3 |
|---|---|
| Boiling Point | 594.9ºC at 760mmHg |
| Melting Point | 201-203°C |
| Molecular Formula | C15H21NO6 |
| Molecular Weight | 311.33000 |
| Flash Point | 313.6ºC |
| Exact Mass | 311.13700 |
| PSA | 108.25000 |
| Index of Refraction | 1.59 |
| InChIKey | SKOZFDIGKDPQBO-QMIVOQANSA-N |
| SMILES | CC(=O)NC1C(OCc2ccccc2)OC(CO)C(O)C1O |
| Storage condition | −20°C |
| Water Solubility | methanol: soluble10mg/mL, clear |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi: Irritant; |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles31
More Articles| Inhibition of CD44 N- and O-linked glycosylation decreases endometrial cell lines attachment to peritoneal mesothelial cells. Fertil. Steril. 95(2) , 823-5, (2011) The attachment of endometrial epithelial cells (EECs) and endometrial stromal cells (ESCs) to peritoneal mesothelial cells (PMCs) with and without inhibition of N- and O-linked glycosylation, the viab... | |
| Antiadhesive character of mucin O-glycans at the apical surface of corneal epithelial cells. Invest. Ophthalmol. Vis. Sci. 49(1) , 197-203, (2008) Prolonged contact of opposite mucosal surfaces, which occurs on the ocular surface, oral cavity, reproductive tract, and gut, requires a specialized apical cell surface that prevents adhesion. The pur... | |
| Benzyl-N-acetyl-alpha-D-galactosaminide induces a storage disease-like phenotype by perturbing the endocytic pathway. J. Biol. Chem. 278(14) , 12374-83, (2003) The sugar analog O-benzyl-N-acetyl-alpha-d-galactosaminide (BG) is an inhibitor of glycan chain elongation and inhibits alpha2,3-sialylation in mucus-secreting HT-29 cells. Long-term exposure of these... |
Synonyms
| MFCD00057920 |
| 16beta-Hydroxydisitoxigenin |
