CAS 358731-15-4|Bis[(2H9)butyl] 1,2-(2H4)benzenedicarboxylate
Introduction：Basic information about CAS 358731-15-4|Bis[(2H9)butyl] 1,2-(2H4)benzenedicarboxylate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Bis[(2H9)butyl] 1,2-(2H4)benzenedicarboxylate | ||
|---|---|---|---|
| CAS Number | 358731-15-4 | Molecular Weight | 300.479 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 337.0±10.0 °C at 760 mmHg |
| Molecular Formula | C16D22O4 | Melting Point | / |
| MSDS | / | Flash Point | 171.1±0.0 °C |
Names
| Name | di-n-butyl phthalate-d22 |
|---|---|
| Synonym | More Synonyms |
BiologicalActivity
| Description | Dibutyl phthalate-d22 is the deuterium labeled Dibutyl phthalate[1]. Dibutyl phthalate is a commonly used plasticizer commonly found in some food packaging materials, personal care products, and the coating of oral medications. May cause toxicity and adverse neurobehavioral effects[2][3][4]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>Others |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Rasmussen LM, et al. Effects of in vitro exposure to dibutyl phthalate, mono-butyl phthalate, and acetyl tributyl citrate on ovarian antral follicle growth and viability. Biol Reprod. 2017 May 1;96(5):1105-1117. [3]. Aly HA, et al. Dibutyl phthalate induces oxidative stress and impairs spermatogenesis in adult rats. Toxicol Ind Health. 2016 Aug;32(8):1467-1477. [4]. Farzanehfar V, et al. Determination of dibutyl phthalate neurobehavioral toxicity in mice. Food Chem Toxicol. 2016 Aug;94:221-6. |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 337.0±10.0 °C at 760 mmHg |
| Molecular Formula | C16D22O4 |
| Molecular Weight | 300.479 |
| Flash Point | 171.1±0.0 °C |
| Exact Mass | 300.289886 |
| PSA | 52.60000 |
| LogP | 4.82 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.499 |
Synonyms
| Bis[(H)butyl] (H)benzene-1,2-dicarboxylate |
| 1,2-Benzene-d-dicarboxylic acid, dibutyl-d ester |
| Bis[(H)butyl] 1,2-(H)benzenedicarboxylate |
