Introduction：Basic information about CAS 157528-81-9|Coronarin D methyl ether, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Coronarin D methyl ether |
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| CAS Number | 157528-81-9 | Molecular Weight | 332.48 |
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| Density | 1.0±0.1 g/cm3 | Boiling Point | 447.8±45.0 °C at 760 mmHg |
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| Molecular Formula | C21H32O3 | Melting Point | / |
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| MSDS | / | Flash Point | 191.7±23.3 °C |
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Names
| Name | (3E)-5-Methoxy-3-{2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedec ahydro-1-naphthalenyl]ethylidene}dihydro-2(3H)-furanone |
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| Synonym | More Synonyms |
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Coronarin D methyl ether BiologicalActivity
| Description | Methoxycoronarin D can be isolated from Hedychium coronarium J. Koenig and is a potent inhibitor of NF-魏B with an IC50 value of 7.3 渭M. Methoxycoronarin D is also a selective inhibitor of COX-1 with an IC50 value of 0.9 渭M[1]. |
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| Related Catalog | Research Areas >>Inflammation/ImmunologySignaling Pathways >>Immunology/Inflammation >>COX |
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| References | [1]. Endringer D C, et al. Cancer chemoprevention activity of labdane diterpenes from rhizomes of Hedychium coronarium[J]. Revista Brasileira de Farmacognosia, 2014, 24: 408-412. |
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Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
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| Boiling Point | 447.8±45.0 °C at 760 mmHg |
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| Molecular Formula | C21H32O3 |
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| Molecular Weight | 332.48 |
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| Flash Point | 191.7±23.3 °C |
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| Exact Mass | 332.235138 |
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| PSA | 35.53000 |
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| LogP | 5.65 |
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| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
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| Index of Refraction | 1.516 |
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| InChIKey | AXVHMYNDGVQIQD-NVNXTCNLSA-N |
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| SMILES | C=C1CCC2C(C)(C)CCCC2(C)C1CC=C1CC(OC)OC1=O |
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Safety Information
Synonyms
| (3E)-5-Methoxy-3-{2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedecahydro-1-naphthalenyl]ethylidene}dihydro-2(3H)-furanone |
| 2(3H)-Furanone, 3-[2-[(1S,4aS,8aS)-decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-5-methoxy-, (3E)- |
| (3Z)-5-Methoxy-3-{2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedecahydro-1-naphthalenyl]ethylidene}dihydro-2(3H)-furanone |
| 2(3H)-Furanone, 3-[2-[(1S,4aS,8aS)-decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-5-methoxy-, (3Z)- |
