Introduction：Basic information about CAS 872363-17-2|Dipraglurant, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Dipraglurant |
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| CAS Number | 872363-17-2 | Molecular Weight | 265.28500 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C16H12FN3 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 6-fluoro-2-(4-pyridin-2-ylbut-3-ynyl)imidazo[1,2-a]pyridine |
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| Synonym | More Synonyms |
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Dipraglurant BiologicalActivity
| Description | Dipraglurant (ADX 48621) is a mGluR5 antagonists with IC50 of 0.021 μM. IC50 Value: 0.021 μM [1]Target: mGluRDipraglurant (ADX-48621) from Addex Therapeutics showed in vivo activity in different anxiety models in rat50 and is currently in phase II for the treatment of dyskinesia in Parkinson's disease. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>mGluRResearch Areas >>Neurological Disease |
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| References | [1]. The Synthesis and Use of Certain Pyridine Derivatives as Modulators of the G-protein Coupled Receptors mGlu5 and P2Y12 |
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Chemical & Physical Properties
| Molecular Formula | C16H12FN3 |
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| Molecular Weight | 265.28500 |
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| Exact Mass | 265.10200 |
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| PSA | 30.19000 |
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| LogP | 2.85270 |
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Synonyms
| Dipraglurant |
| CS-0690 |
| Dipraglurant [INN] |
| UNII-CV8JZR21A1 |
