Introduction：Basic information about CAS 159138-81-5|Cariporide Mesylate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Cariporide Mesylate |
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| CAS Number | 159138-81-5 | Molecular Weight | 379.45200 |
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| Density | / | Boiling Point | 542.8ºC at 760mmHg |
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| Molecular Formula | C13H21N3O6S2 | Melting Point | / |
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| MSDS | / | Flash Point | 282.1ºC |
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Names
| Name | N-(diaminomethylidene)-3-methylsulfonyl-4-propan-2-ylbenzamide,methanesulfonic acid |
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| Synonym | More Synonyms |
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Cariporide Mesylate BiologicalActivity
| Description | Cariporide is a Na+/H+ Exchanger 1 (NHE-1) inhibitor. Cariporide inhibits the expression of monocyte endothelial cell adhesion and intercellular adhesion molecule-1 (ICAM-1) mediated by high glucose (HG) by inhibiting the activation of NHE-1[1]. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>Sodium ChannelResearch Areas >>Cardiovascular DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>Potassium Channel |
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| References | [1]. Wang SX, et al. Cariporide inhibits high glucose-mediated adhesion of monocyte-endothelial cell and expression of intercellular adhesion molecule-1. Life Sci. 2006 Aug 29;79(14):1399-404. |
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Chemical & Physical Properties
| Boiling Point | 542.8ºC at 760mmHg |
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| Molecular Formula | C13H21N3O6S2 |
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| Molecular Weight | 379.45200 |
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| Flash Point | 282.1ºC |
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| Exact Mass | 379.08700 |
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| PSA | 187.73000 |
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| LogP | 3.87720 |
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| Vapour Pressure | 7.62E-12mmHg at 25°C |
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| InChIKey | FNDLQABGYJQJPH-UHFFFAOYSA-N |
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| SMILES | CC(C)c1ccc(C(=O)N=C(N)N)cc1S(C)(=O)=O.CS(=O)(=O)O |
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Synonyms
| 4-isopropyl-3-methylsulfonylbenzoylguanidine methanesulfonate |
| Cariporide mesylate |
| Cariporide mesilate |
| Cariporide mesylate (USAN) |
