Introduction：Basic information about CAS 352439-36-2|Azide-PEG8-alcohol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Azide-PEG8-alcohol |
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| CAS Number | 352439-36-2 | Molecular Weight | 395.44900 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C16H33N3O8 | Melting Point | / |
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| MSDS | USA | Flash Point | / |
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| Symbol |
GHS07 | Signal Word | Warning |
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Names
| Name | 2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol |
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| Synonym | More Synonyms |
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Azide-PEG8-alcohol BiologicalActivity
| Description | Azide-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Molecular Formula | C16H33N3O8 |
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| Molecular Weight | 395.44900 |
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| Exact Mass | 395.22700 |
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| PSA | 134.59000 |
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| InChIKey | BUMODEBRFGPXRM-UHFFFAOYSA-N |
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| SMILES | [N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCO |
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| Storage condition | 2-8°C |
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Safety Information
| Symbol |
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H315-H319-H335 |
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| Precautionary Statements | P261-P305 + P351 + P338 |
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| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
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| Hazard Codes | Xi |
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| Risk Phrases | 36/37/38 |
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| Safety Phrases | 26 |
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| RIDADR | NONH for all modes of transport |
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| HS Code | 2929909090 |
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Customs
| HS Code | 2929909090 |
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| Summary | 2929909090 other compounds with other nitrogen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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Synonyms
| 1-azido-23-hydroxy-3,6,9,12,15,18,21-heptaoxatricosane |
| AmbotzPEG1088 |
| Azido-PEG (n=7) |
| 23-azido-3,6,9,12,15,18,21-heptaoxatricosan-1-ol |
| O-(2-azidoethyl)heptaethyleneglycol |
| 3,6,9,12,15,18,21-Heptaoxatricosan-1-ol,23-azido |
